CXCR2 - C-X-C motif chemokine receptor 2 Gene

Also Known as IL8R2; IL8RB

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100124654

About CXCR2

Primary_assembly 15: 120,219,658-120,231,041 forward strand.Sscrofa11.1:CM000826.5

This gene has 2 transcripts (splice variants), 275 orthologues and 22 paralogues. Biased expression in spleen (RPKM 21.4), lung (RPKM 5.4) and 1 other tissue.

CXCR2 Products (12)

mRNA Protein Name
XM_021075284.1 XP_020930943.1 C-X-C chemokine receptor type 2 isoform X2
XM_021075283.1 XP_020930942.1 C-X-C chemokine receptor type 2 isoform X2
XM_021075281.1 XP_020930940.1 C-X-C chemokine receptor type 2 isoform X1
XM_021075285.1 XP_020930944.1 C-X-C chemokine receptor type 2 isoform X2
XM_021075282.1 XP_020930941.1 C-X-C chemokine receptor type 2 isoform X1
XM_021075280.1 XP_020930939.1 C-X-C chemokine receptor type 2 isoform X1
XM_021075284.1 XP_020930943.1 C-X-C chemokine receptor type 2 isoform X2
XM_021075281.1 XP_020930940.1 C-X-C chemokine receptor type 2 isoform X1
XM_021075280.1 XP_020930939.1 C-X-C chemokine receptor type 2 isoform X1
XM_021075283.1 XP_020930942.1 C-X-C chemokine receptor type 2 isoform X2
XM_021075282.1 XP_020930941.1 C-X-C chemokine receptor type 2 isoform X1
XM_021075285.1 XP_020930944.1 C-X-C chemokine receptor type 2 isoform X2

CXCR2 Protein Structure

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (70 - 97)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (70 - 346)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (104 - 129)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (140 - 170)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (181 - 203)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (229 - 257)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (265 - 295)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (314 - 339)

  • 0
  • 100
  • 200
  • 300
  • 382 a.a.
Protein Preferred Names Protein Names

C-X-C chemokine receptor type 2

  • interleukin 8 receptor 2

  • interleukin 8 receptor, beta

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Phase
HY-15251 Reparixin Inhibitor 99.99% Phase 3
HY-15252 Reparixin L-lysine salt Inhibitor 99.87% Phase 3
HY-19519A Ladarixin sodium Antagonist 99.84% Phase 3
HY-10198 Navarixin Antagonist 99.33% Phase 2
HY-13848 Rugocrixan 99.54% Phase 2
HY-19855 AZD-5069 Antagonist 99.91% Phase 2
HY-119339 SX-682 Inhibitor 99.64% Phase 2
HY-50688 SB-265610 Antagonist 99.03% Phase 2
HY-19768 Danirixin Antagonist 98.19% Phase 2
HY-18263C Elubrixin tosylate Antagonist 98.14% Phase 2
HY-18263A Elubrixin Antagonist / Phase 2

Pre-clinical Phase

Bioactive Molecules (26)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16711 SB225002 Antagonist 99.90% Unkown
HY-120427 Cosalane Antagonist 99.78% Unkown
HY-101407 Nicotinamide N-oxide Antagonist 99.85% Unkown
HY-121983 CAY10594 Modulator 98.64% Unkown
HY-P4846 Ac-Pro-Gly-Pro-OH Agonist 99.49% Unkown
HY-12927 SX-517 Antagonist 99.90% Unkown
HY-10011 SCH 563705 Antagonist 99.86% Unkown
HY-101022 CXCR2-IN-1 Inhibitor 99.54% Unkown
HY-165428 SCH-900875 Inhibitor 98.16% Unkown
HY-120878 CXCR2-IN-2 Antagonist 99.52% Unkown
HY-15462 SRT3109 Antagonist 99.68% Unkown
HY-119259 AZD8309 Antagonist 99.98% Unkown
HY-147392 CXCR2 antagonist 8 Antagonist 98.38% Unkown
HY-181654 Snail IN-1 Inhibitor 98.27% Unkown
HY-13021 SRT3190 Antagonist 99.77% Unkown
HY-101407R Nicotinamide N-oxide (Standard) Antagonist 99.03% Unkown
HY-181681 CXCR2 antagonist 10 Antagonist / Unkown
HY-179387 CXCR2-IN-3 Inhibitor / Unkown
HY-110268 NVP CXCR2 20 Antagonist / Unkown
HY-144784 CXCR2 antagonist 7 Antagonist / Unkown
HY-144780 CXCR2 antagonist 4 Antagonist / Unkown
HY-124056 AZ10397767 Antagonist / Unkown
HY-144781 CXCR2 antagonist 5 Antagonist / Unkown
HY-117823 VUF11418 Agonist / Unkown
HY-144783 CXCR2 antagonist 6 Antagonist / Unkown
HY-N2573 Corydalmine Inhibitor 99.74% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CXCR2 NCBI NCBI:3579