Ryr3 - ryanodine receptor 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170546

Summary

Enables calcium-induced calcium release activity and ryanodine-sensitive calcium-release channel activity. Involved in negative regulation of cytosolic calcium ion concentration. Located in endoplasmic reticulum and perinuclear region of cytoplasm. Orthologous to human RYR3 (ryanodine receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ryr3 Products (1)

mRNA Protein Name
XM_039106806.1 XP_038962734.1 LOW QUALITY PROTEIN: ryanodine receptor 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium-induced calcium release activity IDA
IDA: Inferred from direct assay
18799678 RGD
enables ryanodine-sensitive calcium-release channel activity IDA
IDA: Inferred from direct assay
18799678 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
18799678 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
24692174 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
24692174 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
20177054 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LOW QUALITY PROTEIN: ryanodine receptor 3

ryanodine receptor 3

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12542 Dantrolene Inhibitor 99.93% Yes
HY-12542A Dantrolene sodium hemiheptahydrate Inhibitor 99.79% Unkown
HY-14657 Dantrolene sodium Inhibitor 99.79% Yes

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-149662 TMDJ-035 Inhibitor 99.92% Unkown
HY-113040A (17R,18S)-Epoxyeicosatetraenoic acid Inhibitor 93.0% Unkown
HY-RS12370 RYR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19158 Ryr3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25647 Ryr3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ryr3 NCBI NCBI:6263