Dcn - decorin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29139

Summary

Enables Collagen binding activity and protein N-terminus binding activity. Involved in several processes, including animal organ development; response to lipopolysaccharide; and wound healing. Located in extracellular matrix. Part of Collagen type VI trimer. Biomarker of asthma; myocardial infarction; and obesity. Human ortholog(s) of this gene implicated in breast carcinoma; congenital stromal corneal dystrophy; and high grade glioma. Orthologous to human DCN (decorin). [provided by Alliance of Genome Resources, Apr 2022]

Dcn Products (1)

mRNA Protein Name
NM_024129.1 NP_077043.1 decorin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables collagen binding IDA
IDA: Inferred from direct assay
12840020 RGD
Biological Process GO Annotation Evidence References Source
involved in kidney development IEP
IEP: Inferred from expression pattern
15282150 RGD
involved in placenta development IEP
IEP: Inferred from expression pattern
16987756 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
18471238 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
16525834 RGD
involved in skeletal muscle tissue development IEP
IEP: Inferred from expression pattern
17679144 RGD
Cellular Component GO Annotation Evidence References Source
part of collagen type VI trimer IDA
IDA: Inferred from direct assay
12840020 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

decorin

  • DSPG

  • PG-S2

  • PG40

  • bone proteoglycan II

  • dermatan sulfate proteoglycan-II (decorin)

Recombinant Dcn Proteins

Cat. No. Product Name Accession Purity
HY-P74202 Decorin/PGS2 Protein, Rat (HEK293, His) Q01129 (G17-K354) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (21)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124602 DI-591 Inhibitor 98.36% Unkown
HY-145733 DI-1859 99.62% Unkown
HY-111505 NAcM-OPT Inhibitor 98.69% Unkown
HY-W264347 DCN1-UBC12-IN-4 Inhibitor 95.10% Unkown
HY-126075A WS-383 Inhibitor 99.43% Unkown
HY-161470 WS-384 98.23% Unkown
HY-126075 WS-383 free base Inhibitor / Unkown
HY-122874 DI-404 Inhibitor / Unkown
HY-142691 DCN1-UBC12-IN-1 Inhibitor / Unkown
HY-142692 DCN1-UBC12-IN-3 Inhibitor / Unkown
HY-142694 DCN1-UBC12-IN-2 Inhibitor / Unkown
HY-149980 DCN-83 Inhibitor / Unkown
HY-156240 DI-1548 / Unkown
HY-163014 Dicamba 1-azidopropane / Unkown
HY-169026 DCN1-IN-2 Inhibitor / Unkown
HY-184536 DCN1 modulator-1 Modulator / Unkown
HY-RS03583 DCN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111505A NAcM-OPT hydrochloride Inducer / Unkown
HY-151794 DACN(Ms) hydrochloride / Unkown
HY-RS17215 Dcn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23667 Dcn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dcn NCBI NCBI:1634