DCN1-UBC12-IN-3
DCN1-UBC12-IN-3 is potent and selective DCN1-UBC12 inhibitor with an IC50 of 2.25 nM. Anticardiac fibrotic effect.
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- CAS No.: 2374827-45-7
- Formule: C30H30N8O3S2
- Masse moléculaire:614.74
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Fibroblast of cardiac tissue | IC50 |
25.78 μM
Compound: 49
|
Cytotoxicity against Sprague-Dawley rat cardiac fibroblast by MTT assay
Cytotoxicity against Sprague-Dawley rat cardiac fibroblast by MTT assay
|
[PMID: 34939411] |
In Vitro
DCN1-UBC12-IN-3 (compound 49) possesses low cytotoxicity toward cardiac fibroblasts (CFs) with an IC50 of 25 78 μM for 24 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2374827-45-7
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Masse moléculaire 614.74
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Formule C30H30N8O3S2
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SMILES
N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C4C=CC=CC4=C3)N=C1SC5=NN=NN5CCN(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)