DCN1-IN-2
DCN1-IN-2 is a DCN1 inhibitor with an IC50 value of 2.96 nM. DCN1-IN-2 can alleviate Ang II/TGFβ-induced activation of cardiac fibroblasts. DCN1-IN-2 can reduce ISO-induced cardiac fibrosis and remodeling in mice by selectively inhibiting cullin 3.
For research use only. We do not sell to patients.
- CAS No.: 2543578-57-8
- Formula: C18H14ClF3N4OS
- Molecular Weight:426.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2543578-57-8
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Molecular Weight 426.84
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Formula C18H14ClF3N4OS
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SMILES
O=C(CCN1C(NN=C1C2=CC=C(Cl)C=C2)=S)NC3=CC=CC(C(F)(F)F)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)