HDAC5 - histone deacetylase 5 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 490941

About HDAC5

Primary_assembly 9: 19,957,080-19,994,564 forward strand.ROS_Cfam_1.0:CM025108.1

This gene has 4 transcripts (splice variants), 194 orthologues and 10 paralogues.

HDAC5 Products (7)

mRNA Protein Name
XM_038676295.1 XP_038532223.1 histone deacetylase 5 isoform X4
XM_038676293.1 XP_038532221.1 histone deacetylase 5 isoform X2
XM_038676292.1 XP_038532220.1 histone deacetylase 5 isoform X2
XM_038676296.1 XP_038532224.1 histone deacetylase 5 isoform X5
XM_038676297.1 XP_038532225.1 histone deacetylase 5 isoform X5
XM_038676294.1 XP_038532222.1 histone deacetylase 5 isoform X3
XM_038676291.1 XP_038532219.1 histone deacetylase 5 isoform X1

HDAC5 Protein Structure

ClassIIa_HDAC_Gln-rich-N

ClassIIa_HDAC_Gln-rich-N: cl25407 (86 - 173)

HDAC5

HDAC5: cd10007 (691 - 1107)

  • 0
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  • 800
  • 1000
  • 1123 a.a.
Protein Preferred Names Protein Names

histone deacetylase 5

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14842 Givinostat Inhibitor 98.67% Yes
HY-13322 Pracinostat Inhibitor 99.80% Yes
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Yes
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Yes

Clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-16026 Ricolinostat Inhibitor 99.83% Phase 2
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Phase 2
HY-16012A Domatinostat Inhibitor 99.34% Phase 2
HY-13432 Nanatinostat Inhibitor 99.67% Phase 2
HY-16012 Domatinostat tosylate Inhibitor 99.66% Phase 2
HY-13432A Nanatinostat TFA Inhibitor / Phase 2
HY-10223 CUDC-101 Inhibitor 99.05% Phase 1

Pre-clinical Phase

Bioactive Molecules (44)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18361 TMP195 Inhibitor 99.82% Unkown
HY-13428 Tubacin Inhibitor 97.11% Unkown
HY-18998 LMK-235 Inhibitor 99.61% Unkown
HY-18360 TMP269 Inhibitor 98.16% Unkown
HY-16699 Nexturastat A Inhibitor 98.69% Unkown
HY-119939 CHDI-390576 Inhibitor 98.10% Unkown
HY-115475 SW-100 Inhibitor 99.93% Unkown
HY-112719 BRD 4354 Inhibitor 98.10% Unkown
HY-126330 SS-208 Inhibitor 99.00% Unkown
HY-150109 Purinostat mesylate Inhibitor 99.45% Unkown
HY-135714 Bavarostat Inhibitor 99.51% Unkown
HY-149285 NT160 Inhibitor 99.58% Unkown
HY-143248 KR-39038 Inhibitor 99.68% Unkown
HY-181126 G194-0712 Activator 99.82% Unkown
HY-112719B BRD 4354 ditrifluoroacetate Inhibitor 98.06% Unkown
HY-148624 CHDI-00484077 Inhibitor 98.38% Unkown
HY-117554 BRD9757 Inhibitor 99.75% Unkown
HY-157740 XSJ-10 Inhibitor 95.16% Unkown
HY-149208 HDAC-IN-53 Inhibitor 95.73% Unkown
HY-P10462A SAP15 acetate Inhibitor 98.04% Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-146679 HDAC6-IN-6 Inhibitor / Unkown
HY-183560 HDAC6-IN-82 Inhibitor / Unkown
HY-179019 HDAC-IN-94 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor 98.71% Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-181579 HDAC6-IN-74 Inhibitor / Unkown
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / Unkown
HY-176733 HDAC6-IN-61 Inhibitor / Unkown
HY-15433B Quisinostat hydrochloride Inhibitor / Unkown
HY-176868 Rodin-C Inhibitor / Unkown
HY-146351 HDAC-IN-38 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-184203 SM-06-09 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-147934 HDAC8-IN-3 Inhibitor / Unkown
HY-P10462 SAP15 Inhibitor / Unkown
HY-175030 TNI-97 Inhibitor / Unkown
HY-184574 HDAC-IN-104 Inhibitor / Unkown
HY-124946 C1A Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HDAC5 NCBI NCBI:10014