CHDI-00484077
Based on 1 Customer Validation
CHDI-00484077 (Compound 12) is a CNS-penetrant class IIa HDAC inhibitor, with IC50s of 0.01 μM (HDAC4), 0.02 μM(HDAC5), 0.02 μM (HDAC7), 0.03 μM (HDAC9) respectively. CHDI-00484077 can be used for research of huntington’s disease.
For research use only. We do not sell to patients.
- Purity: 98.38%
- CAS No.: 3025894-92-9
- Formula: C18H21F3N4O2
- Molecular Weight:382.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC4 0.01 μM (IC50) |
HDAC5 0.02 μM (IC50) |
HDAC7 0.02 μM (IC50) |
HDAC9 0.03 μM (IC50) |
HDAC1 17 μM (IC50) |
HDAC2 27 μM (IC50) |
HDAC3 10 μM (IC50) |
HDAC8 2.0 μM (IC50) |
HDAC6 22 μM (IC50) |
Chemical Information
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CAS No. 3025894-92-9
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Appearance Solid
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Molecular Weight 382.38
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Formula C18H21F3N4O2
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Color White to off-white
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SMILES
FC(F)(C1=NC(C2=CC=C(C=C2)C(N[C@H](C)CN3[C@H](CCC3)C)=O)=NO1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CHDI-00484077 Related Classifications
HY-148624 Related Classifications
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