(S)-Trichostatin A
(S)-Trichostatin A ((S)-TSA) is a HDAC6-selective inhibitor with IC50s of 9.88 nM and 11.1 nM for Zebrafish HDAC6 and Human HDAC6, respectively. (S)-Trichostatin A weakly inhibits other human HDACs.
For research use only. We do not sell to patients.
- CAS No.: 122292-85-7
- Formula: C17H22N2O3
- Molecular Weight:302.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
|
hHDAC6 11.1 nM (IC50) |
Zebrafish HDAC6 9.88 nM (IC50) |
hHDAC1 206.3 nM (IC50) |
hHDAC2 612.65 nM (IC50) |
hHDAC3 320.8 nM (IC50) |
hHDAC4 6341 nM (IC50) |
hHDAC5 6325 nM (IC50) |
hHDAC7 1823.5 nM (IC50) |
hHDAC8 312.2 nM (IC50) |
hHDAC9 4824 nM (IC50) |
hHDAC10 403.35 nM (IC50) |
hHDAC11 2684 nM (IC50) |
Chemical Information
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CAS No. 122292-85-7
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Molecular Weight 302.37
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Formula C17H22N2O3
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SMILES
ONC(/C=C/C(C)=C/[C@H](C)C(C1=CC=C(C=C1)N(C)C)=O)=O
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Synonyms
(S)-TSA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-Trichostatin A Related Classifications
HY-15144B Related Classifications
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