122292-85-7
122292-85-7
Chemical Structure
(S)-Trichostatin A
Synonym(s): (S)-TSA
- CAS No.: 122292-85-7
- Formula:C17H22N2O3
- Molecular Weight:302.37
IUPAC Name: (S,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
InChIKey: RTKIYFITIVXBLE-LEJRBOCMSA-N
SMILES: ONC(/C=C/C(C)=C/[C@H](C)C(C1=CC=C(C=C1)N(C)C)=O)=O
Biological Activity: (S)-Trichostatin A ((S)-TSA) is a HDAC6-selective inhibitor with IC50s of 9.88 nM and 11.1 nM for Zebrafish HDAC6 and Human HDAC6, respectively. (S)-Trichostatin A weakly inhibits other human HDACs[1].
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(S)-Trichostatin A | (S)-Trichostatin A ((S)-TSA) is a HDAC6-selective inhibitor with IC50s of 9.88 nM and 11.1 nM for Zebrafish HDAC6 and Human HDAC6, respectively. (S)-Trichostatin A weakly inhibits other human HDACs. | |||||||||||||||||||||
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References
Keywords
