HDAC6-IN-61
HDAC6-IN-61 (Compound 4e) is a HDAC6 inhibitor (IC50: 73 nM) with selectivity over other HDAC isoforms. HDAC6-IN-61 is also a GPR40 activator. HDAC6-IN-61 increases acetylated tubulin and ERK phosphorylation levels. HDAC6-IN-61 can be used for research of neuroinflammation such as Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C18H18N2O2S
- Molecular Weight:326.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC6 73 nM (IC50) |
HDAC1 1310 nM (IC50) |
HDAC2 2353 nM (IC50) |
HDAC3 626 nM (IC50) |
HDAC5 73 nM (IC50) |
HDAC8 2413 nM (IC50) |
Chemical Information
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Molecular Weight 326.41
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Formula C18H18N2O2S
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SMILES
O=C(NO)CCC1=CC=C(C=C1)NCC2=CC3=C(S2)C=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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