2. Gene
  3. PFDN5 - prefoldin subunit 5 Gene

PFDN5 - prefoldin subunit 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MM1; MM-1; PFD5

Gene ID: 5204 | Gene type: protein coding

About PFDN5

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:53,295,542-53,299,450 (from NCBI)

This gene has 27 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in ovary (RPKM 223.5), thyroid (RPKM 192.0) and 25 other tissues.

Summary

This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

PFDN5 Products(2)

mRNA Protein Name
NM_002624.4 NP_002615.2 prefoldin subunit 5 isoform alpha
NM_145897.3 NP_665904.1 prefoldin subunit 5 isoform gamma

PFDN5 Protein Structure

Prefoldin

Prefoldin: Prefoldin subunit (22 - 141)

  • 0
  • 100
  • 154 a.a.
Protein Preferred Names Protein Names

prefoldin subunit 5

c-myc binding protein

Recombinant PFDN5 Proteins

Cat. No. Product Name Accession Purity
HY-P76542 PFDN5 Protein, Human (His) Q99471 (M1-A154) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10359 PFDN5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PFDN5 RGD RGD:1311436
Bos taurus PFDN5 VGNC VGNC:32767
Canis familiaris PFDN5 VGNC VGNC:97212
Mus musculus PFDN5 MGD MGI:1928753
Macaca mulatta PFDN5 VGNC VGNC:100086
Others PFDN5 NCBI