IL17RD - interleukin 17 receptor D Gene

Also Known as SEF; HH18; IL-17RD; IL17RLM

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54756

About IL17RD

Cytogenetic location: 3p14.3 Genomic coordinates (GRCh38): 3:57,089,982-57,170,317 (from NCBI)

This gene has 7 transcripts (splice variants), 203 orthologues, 4 paralogues and is associated with 2 phenotypes. Broad expression in endometrium (RPKM 8.3), testis (RPKM 6.2) and 14 other tissues.

Summary

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects Fibroblast Growth Factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]

IL17RD Products (2)

mRNA Protein Name
NM_001318864.2 NP_001305793.1 interleukin-17 receptor D isoform b
NM_017563.5 NP_060033.3 interleukin-17 receptor D isoform a precursor

IL17RD Protein Structure

SEFIR

SEFIR: SEFIR domain (356 - 511)

  • 0
  • 200
  • 400
  • 600
  • 739 a.a.
Protein Preferred Names Protein Names

interleukin-17 receptor D

  • IL-17 receptor D

Recombinant IL17RD Proteins

Cat. No. Product Name Accession Purity
HY-P72578 IL-17RD Protein, Human (HEK293, His) Q8NFM7-1 (C17-R299) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Hypogonadotropic Hypogonadism 18 With Or Without Anosmia

  • HH18

  • Hypogonadism, Hypogonadotropic, Type 18 With/Without Anosmia
Kallmann Syndrome

  • Hypogonadism With Anosmia

  • Kallman'S Syndrome

  • Anosmic Hypogonadism

  • Anosmic Idiopathic Hypogonadotropic Hypogonadism

  • Hypogonadotropic Hypogonadism And Anosmia

  • Hypogonadotropic Hypogonadism-Anosmia Syndrome

  • Olfacto-Genital Pathological Sequence

  • Familial Hypogonadism With Anosmia

  • Kallman Syndrome

  • Dysplasia Olfactogenitalis Of De Morsier

  • Kallmann'S Syndrome

  • Congenital Hypogonadotropic Hypogonadism With Anosmia
Arteriovenous Malformations Of The Brain

  • Cerebral Arteriovenous Malformation

  • Intracranial Arteriovenous Malformation

  • Intracranial Hemorrhage In Brain Cerebrovascular Malformations, Susceptibility To

  • Intracranial Arteriovenous Malformations

  • Bavm

  • Cerebral Arteriovenous Malformations

  • Intracranial Hemorrhage In Brain Cerebrovascular Malformations

  • Arteriovenous Malformation Of The Brain, Somatic

  • Intracranial Avm

  • Arteriovenous Malformations Cerebral
Hypogonadotropic Hypogonadism

  • Klinefelter Syndrome

  • Klinefelter'S Syndrome

  • Xxy Syndrome

  • Xxy Trisomy

  • Hypogonadotropism

  • 47, Xxy

  • Congenital Idiopathic Hypogonadotropic Hypogonadism

  • Isolated Congenital Gonadotropin Deficiency

  • 47,Xxy Syndrome

  • 47, Xxy Syndrome

  • Klinefelters Syndrome

  • Hypogonadism

  • Klinefelter Syndrome In Males

  • Klinefelter Syndrome, Unspecified

  • Klinefelter Syndrome Karyotype 47, Xxy
Hypogonadism
Seborrheic Infantile Dermatitis

  • Cradle Cap

  • Infantile Seborrhoeic Dermatitis

  • Seborrhoea Capitis

  • Seborrhoeic Dermatitis Of Scalp

  • Seborrhoeic Eczema Of Scalp

  • Complement 5 Dysfunction

  • Generalized Seborrheic Dermatitis Of Infants

  • Infantile Seborrheic Dermatitis

  • Pityriasis Capitis

  • Seborrhea Capitis

  • Seborrhea Sicca

  • Dandruff

  • Complement Component 5 Deficiency

  • Seborrheic Dermatitis

  • Seborrheic Dermatitis Of Scalp

  • Scurfiness Of Scalp

  • Seborrheic Dermatitis Of Infancy

  • Infantile Seborrhoeic Eczema

  • Neonatal Seborrhoeic Dermatitis

  • Infantile Seborrhoeic Dermatitis Of The Scalp
Sensorineural Hearing Loss

  • Sensory Hearing Loss

  • Sensorineural Deafness

  • Sensorineural Hearing Loss Disorder

  • Hearing Loss, Sensorineural

  • Central Hearing Loss

  • High Frequency Deafness

  • High Frequency Hearing Loss

  • High-Frequency Hearing Loss

  • Perceptive Deafness

  • Perceptive Hearing Loss

  • Perceptive Hearing Loss Or Deafness

  • Hearing Loss Sensorineural

  • Deafness Sensorineural

  • Hearing Loss High-Frequency

  • Hearing Loss, Central

  • Hearing Loss, High-Frequency
Double Outlet Right Ventricle

  • Double Outlet Right Ventricle With Subpulmonary Ventricular Septal Defect

  • Taussig-Bing Syndrome

  • Dextrotransposition Of Aorta

  • Taussig-Bing Syndrome Or Defect

  • Dorv

  • Dorv With Subpulmonary Vsd

  • Dorv-Tga

  • Double Outlet Right Ventricle With Transposition Of The Great Arteries

  • Double Outlet Right Ventricle With Subpulmonary Interventricular Communication, Transposition Type

  • Taussig-Bing Heart

  • Taussig-Bing Malformation

  • Taussig-Bing Complex

  • Taussig-Bing Defect

  • Taussig-Bing

  • Double Outlet Right Ventricle With Remote Ventricular Septal Defect

  • Double Outlet Right Ventricle With Uncommitted Ventricular Septal Defect

  • Double Outlet Right Ventricle With Non-Committed Interventricular Communication

  • Double Outlet Right Ventricle With Subaortic Or Doubly Committed Interventricular Communication Without Pulmonary Stenosis

  • Double Outlet Right Ventricle With Subaortic Or Doubly Committed Interventricular Communication And Pulmonary Stenosis
Renal Hypodysplasia/Aplasia 1

  • Renal Agenesis

  • Renal Adysplasia

  • Renal Aplasia

  • RHDA1

  • Hereditary Renal Aplasia

  • Hra

  • Hereditary Urogenital Adysplasia

  • Hypodysplasia/Aplasia, Renal, Type 1

  • Congenital Absence Of Kidneys Syndrome

  • Congenital Absence Of Kidney

  • Aplastic Kidney
Cryptorchidism, Unilateral Or Bilateral

  • Cryptorchidism

  • Undescended Testicle

  • Undescended Testis

  • Cryptorchism

  • Undescended Testicles

  • CRYPTO

  • Impaired Testicular Descent

  • Cryptosporidiosis

  • Retained Testis

  • Unilateral Cryptorchidism

  • Unilateral Undescended Testis

  • Nondescent Unilateral Testicle

  • Unilateral Cryptorchism

  • Ectopic Testis, Unilateral

  • Bilateral Cryptorchidism

  • Bilateral Cryptorchism

  • Bilateral Nondescent Testicle

  • Bilateral Undescended Testes

  • Bilateral Ectopic Testes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06705 IL17RD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20167 Il17rd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26671 Il17rd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IL17RD RGD RGD:1565237
Macaca mulatta IL17RD VGNC VGNC:73614
Canis familiaris IL17RD VGNC VGNC:41949
Mus musculus IL17RD MGD MGI:2159727
Bos taurus IL17RD VGNC VGNC:30124
Felis catus IL17RD VGNC VGNC:62904
Others IL17RD NCBI