Ywhab - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 56011

Summary

Enables protein C-terminus binding activity. Involved in negative regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Part of transcription repressor complex. Used to study visual epilepsy. Biomarker of brain ischemia. Orthologous to human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta). [provided by Alliance of Genome Resources, Apr 2022]

Ywhab Products (1)

mRNA Protein Name
NM_019377.2 NP_062250.1 14-3-3 protein beta/alpha
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10644344 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
12786973 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
18460465 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
12786973 RGD
part of transcription repressor complex IDA
IDA: Inferred from direct assay
18460465 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

14-3-3 protein beta/alpha

  • 14-3-3 protein beta-subtype

  • 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide

  • KCIP-1

  • prepronerve growth factor RNH-1

  • protein kinase C inhibitor protein 1

  • tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation prot

Orthologs Information

Species Symbol Source ID
Homo sapiens Ywhab NCBI NCBI:7529