2. Gene
  3. DNMT1 - DNA methyltransferase 1 Gene

DNMT1 - DNA methyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 606746 | Gene type: protein coding

About DNMT1

Primary_assembly 2: 68,981,566-69,029,844 reverse strand.Sscrofa11.1:CM000813.5

This gene has 2 transcripts (splice variants), 215 orthologues and 1 paralogue. Broad expression in ovary (RPKM 27.9), heart (RPKM 22.) and 8 other tissues.

DNMT1 Products(1)

mRNA Protein Name
NM_001032355.1 NP_001027526.1 DNA (cytosine-5)-methyltransferase 1

DNMT1 Protein Structure

DMAP_binding

DMAP_binding: pfam06464 (49 - 138)

DNMT1-RFD

DNMT1-RFD: pfam12047 (428 - 563)

zf-CXXC

zf-CXXC: pfam02008 (673 - 719)

BAH_Dnmt1_I

BAH_Dnmt1_I: cd04760 (782 - 905)

BAH_Dnmt1_II

BAH_Dnmt1_II: cd04711 (993 - 1129)

Dcm

Dcm: COG0270 (1166 - 1624)

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  • 1665 a.a.
Protein Preferred Names Protein Names

DNA (cytosine-5)-methyltransferase 1

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0004 Decitabine Inhibitor 99.97% Yes
HY-10586 5-Azacytidine Inhibitor 99.91% Yes
HY-B2194 γ-Oryzanol Inhibitor 99.66% Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15229 Guadecitabine sodium Inhibitor 99.97% Phase 3
HY-112288 C188-9 Inhibitor 99.84% Phase 2
Pre-clinical Phase
Bioactive Molecules (24)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135146 GSK-3484862 Inhibitor 99.95% Unkown
HY-13642 RG108 Inhibitor 99.93% Unkown
HY-13962 SGI-1027 Inhibitor 99.79% Unkown
HY-13420 Zebularine Inhibitor 99.49% Unkown
HY-B2230 Hinokitiol Inhibitor 99.83% Unkown
HY-101925 CM-272 Inhibitor 98.70% Unkown
HY-12746 DC-05 Inhibitor 99.04% Unkown
HY-139015 5-Aza-4'-thio-2'-deoxycytidine Inhibitor 99.89% Unkown
HY-117421A CM-579 trihydrochloride Inhibitor 97.00% Unkown
HY-139664A (R)-GSK-3685032 Inhibitor 98.97% Unkown
HY-12747 DC_517 Inhibitor 99.33% Unkown
HY-173002 MS9024 Degrader 99.83% Unkown
HY-117421 CM-579 Inhibitor / Unkown
HY-179409 MC3817 Inhibitor / Unkown
HY-19826 Isofistularin-3 Inhibitor / Unkown
HY-182009 DNMT-IN-6 Inhibitor / Unkown
HY-179409A MC3817 free base Inhibitor / Unkown
HY-13642G RG108 (GMP) Inhibitor / Unkown
HY-172217 DNMT1-IN-5 Inhibitor / Unkown
HY-181955 MS1129 Degrader / Unkown
HY-182956 DNMT1 Degrader-1 Degrader / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-175988 DNMT/HDAC-IN-2 Inhibitor / Unkown
HY-161694 DNMT1-IN-3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DNMT1 NCBI NCBI:1786