GSK3830052
GSK3830052 is a selective DNA methyltransferase 1 (DNMT1) inhibitor. GSK3830052 can be used to study cancer, sickle cell disease, β-thalassemia, and other diseases associated with DNMT1 inhibition.
For research use only. We do not sell to patients.
- CAS No.: 2170141-06-5
- Formula: C22H28N6O2S2
- Molecular Weight:472.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA Methyltransferase Isoforms
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Biological Activity
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DNMT1 |
GSK3830052 (Compound 471) is a selective DNA methyltransferase 1 (DNMT1) inhibitor. DNMT1 is a maintenance DNA methyltransferase in the core of mammals, responsible for "copying" the methylation pattern of the parent strand to the daughter strand after DNA replication, ensuring the stable transmission of epigenetic information during cell division[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2170141-06-5
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Molecular Weight 472.63
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Formula C22H28N6O2S2
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SMILES
N#CC1=C(SCC2=CC=C(N(S(=O)(C)=O)C)C=C2)N=C(N(CCNC)C)C(C#N)=C1CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)