Cep57 - centrosomal protein 57 Gene

Also Known as Tsp57; mKIAA0092; 3110002L15Rik; 4921510P06Rik; 4931428M20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74360

Summary

Enables microtubule binding activity. Involved in protein homooligomerization. Acts upstream of or within spermatid development. Located in centrosome; cytoplasm; and nucleus. Is expressed in midbrain ventricular layer and telencephalon ventricular layer. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 2. Orthologous to human CEP57 (centrosomal protein 57). [provided by Alliance of Genome Resources, Apr 2022]

Cep57 Products (2)

mRNA Protein Name
NM_001310721.1 NP_001297650.1 centrosomal protein of 57 kDa isoform 2
NM_026665.4 NP_080941.3 centrosomal protein of 57 kDa isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
18294141 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12954732 MGI
Biological Process GO Annotation Evidence References Source
involved in protein homooligomerization IPI
IPI: Inferred from physical interaction
18294141 MGI
involved in spermatid development IEP
IEP: Inferred from expression pattern
12954732 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
18294141 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12954732 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12954732 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

centrosomal protein of 57 kDa

  • testis-specific protein 57

  • translokin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02518 CEP57 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18654 Cep57 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25140 Cep57 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cep57 NCBI NCBI:9702