CXCR2 - C-X-C motif chemokine receptor 2 Gene

Also Known as IL8RB; CXC-R2; CXCR-2

Species: Bos taurus

Gene Type: protein coding
Gene ID: 782719

About CXCR2

Primary_assembly 2: 106,185,020-106,192,570 forward strand.ARS-UCD1.2:CM008169.2

This gene has 2 transcripts (splice variants), 267 orthologues and 24 paralogues.

CXCR2 Products (1)

mRNA Protein Name
NM_001101285.1 NP_001094755.1 C-X-C chemokine receptor type 2

CXCR2 Protein Structure

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (89 - 115)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (89 - 364)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (122 - 147)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (158 - 188)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (199 - 221)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (247 - 275)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (283 - 313)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (332 - 357)

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  • 300
  • 400 a.a.
Protein Preferred Names Protein Names

C-X-C chemokine receptor type 2

  • IL-8R B

  • chemokine receptor CXCR2

  • high affinity interleukin-8 receptor B

  • interleukin 8 receptor, alpha

  • interleukin 8 receptor, beta

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Phase
HY-15251 Reparixin Inhibitor 99.99% Phase 3
HY-15252 Reparixin L-lysine salt Inhibitor 99.87% Phase 3
HY-19519A Ladarixin sodium Antagonist 99.84% Phase 3
HY-10198 Navarixin Antagonist 99.33% Phase 2
HY-13848 Rugocrixan 99.54% Phase 2
HY-19855 AZD-5069 Antagonist 99.91% Phase 2
HY-119339 SX-682 Inhibitor 99.64% Phase 2
HY-50688 SB-265610 Antagonist 99.03% Phase 2
HY-19768 Danirixin Antagonist 98.19% Phase 2
HY-18263C Elubrixin tosylate Antagonist 98.14% Phase 2
HY-18263A Elubrixin Antagonist / Phase 2

Pre-clinical Phase

Bioactive Molecules (26)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16711 SB225002 Antagonist 99.90% Unkown
HY-120427 Cosalane Antagonist 99.78% Unkown
HY-101407 Nicotinamide N-oxide Antagonist 99.85% Unkown
HY-121983 CAY10594 Modulator 98.64% Unkown
HY-P4846 Ac-Pro-Gly-Pro-OH Agonist 99.49% Unkown
HY-12927 SX-517 Antagonist 99.90% Unkown
HY-10011 SCH 563705 Antagonist 99.86% Unkown
HY-101022 CXCR2-IN-1 Inhibitor 99.54% Unkown
HY-165428 SCH-900875 Inhibitor 98.16% Unkown
HY-120878 CXCR2-IN-2 Antagonist 99.52% Unkown
HY-15462 SRT3109 Antagonist 99.68% Unkown
HY-119259 AZD8309 Antagonist 99.98% Unkown
HY-147392 CXCR2 antagonist 8 Antagonist 98.38% Unkown
HY-181654 Snail IN-1 Inhibitor 98.27% Unkown
HY-13021 SRT3190 Antagonist 99.77% Unkown
HY-101407R Nicotinamide N-oxide (Standard) Antagonist 99.03% Unkown
HY-181681 CXCR2 antagonist 10 Antagonist / Unkown
HY-179387 CXCR2-IN-3 Inhibitor / Unkown
HY-110268 NVP CXCR2 20 Antagonist / Unkown
HY-144784 CXCR2 antagonist 7 Antagonist / Unkown
HY-144780 CXCR2 antagonist 4 Antagonist / Unkown
HY-124056 AZ10397767 Antagonist / Unkown
HY-144781 CXCR2 antagonist 5 Antagonist / Unkown
HY-117823 VUF11418 Agonist / Unkown
HY-144783 CXCR2 antagonist 6 Antagonist / Unkown
HY-N2573 Corydalmine Inhibitor 99.74% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CXCR2 NCBI NCBI:3579