2. Gene
  3. PIP5K1B - phosphatidylinositol-4-phosphate 5-kinase type 1 beta Gene

PIP5K1B - phosphatidylinositol-4-phosphate 5-kinase type 1 beta Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MSS4; STM7

Gene ID: 8395 | Gene type: protein coding

About PIP5K1B

Cytogenetic location: 9q21.11 Genomic coordinates (GRCh38): 9:68,705,240-69,009,176 (from NCBI)

This gene has 8 transcripts (splice variants), 275 orthologues and 6 paralogues. Broad expression in colon (RPKM 8.2), duodenum (RPKM 7.6) and 20 other tissues.

Summary

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in regulation of phosphatidylinositol 3-kinase signaling. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in uropod. [provided by Alliance of Genome Resources, Apr 2022]

PIP5K1B Products(7)

mRNA Protein Name
NM_001278253.2 NP_001265182.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3
NM_001376036.1 NP_001362965.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2
NM_001376037.1 NP_001362966.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2
NM_001376039.1 NP_001362968.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2
NM_001376040.1 NP_001362969.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3
NM_001376041.1 NP_001362970.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3
NM_003558.4 NP_003549.1 phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2

PIP5K1B Protein Structure

PIP5K

PIP5K: Phosphatidylinositol-4-phosphate 5-Kinase (108 - 393)

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  • 540 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 4-phosphate 5-kinase type-1 beta

PIP5K1-beta

Related Diseases

Diseases Alias
Friedreich Ataxia

Friedreich Ataxia 1

FRDA

Friedreich Ataxia With Retained Reflexes

Frda1

Fa

Friedreich'S Ataxia

Hereditary Spinal Ataxia

Fa1

Friedreich'S Tabes

Hereditary Spinal Sclerosis

Spinocerebellar Ataxia, Friedreich

Friedreich Spinocerebellar Ataxia

Friedrich'S Ataxia
Friedreich Ataxia 2

FRDA2

Friedreich Ataxia, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10567 PIP5K1B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PIP5K1B VGNC VGNC:32911
Macaca mulatta PIP5K1B VGNC VGNC:76001
Mus musculus PIP5K1B MGD MGI:107930
Felis catus PIP5K1B VGNC VGNC:68862
Rattus norvegicus PIP5K1B RGD RGD:1310914
Canis familiaris PIP5K1B VGNC VGNC:44575