2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. GSK248233A

GSK248233A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 1.03 μM and 2 nM, respectively. GSK248233A also shows activity against the AGC family. GSK248233A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays.

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GSK248233A

GSK248233A 화학구조

CAS No. : 850665-21-3

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GSK248233A Related Antibodies

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VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

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제품 설명

GSK248233A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 1.03 μM and 2 nM, respectively. GSK248233A also shows activity against the AGC family. GSK248233A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].

Cellular Effect
Cell Line Type Value Description References
Sf9 IC50
2 nM
Compound: 6h
Inhibition of human ROCK1 in Sf9 cells
Inhibition of human ROCK1 in Sf9 cells
[PMID: 17201404]
분자량

484.51

화학식

C25H24N8O3
CAS No.
SMILES

O=C(C1=CC=C(N(C)C)C=C1)NC2=CC(OC3=CC(N(CC)C(C4=NON=C4N)=N5)=C5C=N3)=CC=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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GSK248233A Related Classifications

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  • 농도 희석 계산기

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK248233A850665-21-3VEGFRVascular endothelial growth factor receptorInhibitorinhibitorinhibit

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상품명:
GSK248233A
Cat. No.:
HY-160686
수량:
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