JNJ-27390467
JNJ-27390467 is a potent, orally active, and selective tryptase inhibitor (human β-tryptase IC50 = 3.6 nM, Ki = 3.7 nM). JNJ-27390467 exhibits excellent selectivity over trypsin of ~5000-fold. JNJ-27390467 shows effects in animal models of airway inflammation. JNJ-27390467 can be used for allergic asthma research.
For research use only. We do not sell to patients.
- CAS No.: 1025795-12-3
- Formula: C33H30N2O5
- Molecular Weight:534.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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human β-tryptase 3.6 nM (IC50) |
human β-tryptase 3.7 nM (Ki) |
Chemical Information
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CAS No. 1025795-12-3
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Molecular Weight 534.60
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Formula C33H30N2O5
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SMILES
NCC1=CC=C(OCC23CCN(C(C4=CC=C(C#CC5=CC=CC=C5)O4)=O)CC3)C2=C1.OC(C6=CC=CC=C6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNJ-27390467 Related Classifications
HY-14515 Related Classifications
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