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製品番号: HY-W036566

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2-Phenylcyclopropanamine

2-Phenylcyclopropanamine (Compound 3) is an irreversible inhibitor of MAO-A/B and LSD1. 2-Phenylcyclopropanamine shows no activity against LOXL2.

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純度 : 98.83%
CAS 番号: 54-97-7
分子式: C₉H₁₁N
分子量:133.19

保管条件:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

2-Phenylcyclopropanamine 構造式

CAS 番号: 54-97-7

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

2-Phenylcyclopropanamine (Compound 3) is an irreversible inhibitor of MAO-A/B and LSD1. 2-Phenylcyclopropanamine shows no activity against LOXL2^[1].

Monoamine Oxidase アイソフォーム固有の製品をすべて表示 :

MAO-A
MAO-B

Histone Demethylase アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	GI₅₀	553 μM Compound: PCPA	Antiproliferative activity against human HL-60 cells incubated for 3 days by alamar blue assay Antiproliferative activity against human HL-60 cells incubated for 3 days by alamar blue assay	[PMID: 38340642]
HMEC	IC₅₀	1420 μM Compound: PCPA	Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay Cytotoxicity against HMEC cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay	[PMID: 36262394]
MDA-MB-231	GI₅₀	798 μM Compound: PCPA	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 3 days by alamar blue assay	[PMID: 36262394]
LN-18	GI₅₀	303 μM Compound: PCPA	Antiproliferative activity against human LN-18 cells incubated for 3 days by alamar blue assay Antiproliferative activity against human LN-18 cells incubated for 3 days by alamar blue assay	[PMID: 38340642]
PC-3	GI₅₀	559 μM Compound: PCPA	Antiproliferative activity against human PC-3 cells incubated for 3 days by alamar blue assay Antiproliferative activity against human PC-3 cells incubated for 3 days by alamar blue assay	[PMID: 38340642]
PrEC	GI₅₀	1064 μM Compound: PCPA	Cytotoxicity against human PrEC cells incubated for 3 days by alamar blue assay Cytotoxicity against human PrEC cells incubated for 3 days by alamar blue assay	[PMID: 38340642]

化学情報

CAS 番号 54-97-7
性状 Solid
分子量 133.19
分子式 C₉H₁₁N
SMILES

NC1CC1C2=CC=CC=C2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

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- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Hutchinson JH, et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX. ACS medicinal chemistry letters. 2017 Apr 13;8(4):423-427. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
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化学情報
純度とドキュメンテーション
参考文献

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2-Phenylcyclopropanamine

Monoamine Oxidase アイソフォーム固有の製品をすべて表示

Histone Demethylase アイソフォーム固有の製品をすべて表示