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Puromycin (dihydrochloride)

(別名: ピューロマイシン二塩酸塩; CL13900 (dihydrochloride))
436 Cited Publications
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Based on 436 publication(s) in Google Scholar

Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis.

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  • 純度: 99.93%
  • CAS 番号: 58-58-2
  • 分子式: C22H31Cl2N7O5
  • 分子量:544.43
  • 保管条件:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)

  • Puromycin dihydrochloride Chemical Structure
    Puromycin dihydrochloride 構造式
  • Experimental Validation Results for Puromycin dihydrochloride
  • Experimental Validation Results for Puromycin dihydrochloride
  • Experimental Validation Results for Puromycin dihydrochloride
  • Experimental Validation Results for Puromycin dihydrochloride
CAS 番号: 58-58-2
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  • Puromycin dihydrochloride Chemical Structure
    Puromycin dihydrochloride Chemical Structure
    1/16
  • 1/16

    Puromycin dihydrochloride purchased from MedChemExpress. Usage Cited in: Autophagy. 2025 Jun;21(6):1192-1211. [Abstract]

    Customer Validation
     Wild-type or mutated A549 cells subjected to the indicated treatments were stably transfected with a puromycin-inducible GFP-LC3 lentivirus at an MOI of 5. Autophagosomes levels were represented by the presence of GFP-LC3 in cells (A scale bar: 10 μm; B scale bar: 20 μm) (left panel).

  • 1/16

    Puromycin dihydrochloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2024 Nov 6;15(1):9578. [Abstract]

    Customer Validation
     Viral titers of supernatants from Huh7.0 FAM134B WT cells, Huh7.0 FAM134B KO cells, Huh7.0 FAM134B KO cells (1 μg/mL, 48 h) stably expressing FAM134BWT or Huh7.0 FAM134B KO cells stably expressing FAM134BR142A, infected with ZIKV at an MOI of 1 for 72 h, quantified by plaque assay.

  • 1/16

    Puromycin dihydrochloride purchased from MedChemExpress. Usage Cited in: Mol Cell. 2023 Dec 21;83(24):4494-4508.e6. [Abstract]

    Customer Validation
     Global protein synthesis analyzed by puromycin dihydrochloride (4 d) labeling assay upon METTL14 knockdown in HeLa cells. Silencing of EIF3A serves as a positive control.

  • 1/16

    Puromycin dihydrochloride purchased from MedChemExpress. Usage Cited in: Mol Cell. 2023 Dec 21;83(24):4494-4508.e6. [Abstract]

    Customer Validation
     Global protein synthesis analyzed by puromycin dihydrochloride (4 d) labeling assay upon IGF2BP1-3 knockdown in HeLa cells.

  • Puromycin dihydrochloride