BACE2-IN-1
Based on 1 Customer Validation
BACE2-IN-1 (compound 3l) is a highly selective BACE2 inhibitor with a Ki value of 1.6 nM. BACE2 inhibitors can be used to research of Type 2 Diabetes.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.4%
- CAS 番号: 1676107-08-6
- 分子式: C36H38F3N3O3
- 分子量:617.70
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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BACE2 1.6 nM (Ki) |
BACE1 815.1 nM (Ki) |
化学情報
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CAS 番号 1676107-08-6
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性状 Solid
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分子量 617.70
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分子式 C36H38F3N3O3
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Color White to off-white
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SMILES
O=C(C1=CC(C)=CC(C(N[C@@H](CC2=CC=CC=C2)[C@H](O)CNCC3=CC=CC(C(F)(F)F)=C3)=O)=C1)N(C)[C@@H](C4=CC=CC=C4)C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 62 mg/mL (100.37 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.6189 mL | 8.0945 mL | 16.1891 mL | 40.4727 mL |
| 5 mM | 0.3238 mL | 1.6189 mL | 3.2378 mL | 8.0945 mL | |
| 10 mM | 0.1619 mL | 0.8095 mL | 1.6189 mL | 4.0473 mL | |
| 15 mM | 0.1079 mL | 0.5396 mL | 1.0793 mL | 2.6982 mL | |
| 20 mM | 0.0809 mL | 0.4047 mL | 0.8095 mL | 2.0236 mL | |
| 25 mM | 0.0648 mL | 0.3238 mL | 0.6476 mL | 1.6189 mL | |
| 30 mM | 0.0540 mL | 0.2698 mL | 0.5396 mL | 1.3491 mL | |
| 40 mM | 0.0405 mL | 0.2024 mL | 0.4047 mL | 1.0118 mL | |
| 50 mM | 0.0324 mL | 0.1619 mL | 0.3238 mL | 0.8095 mL | |
| 60 mM | 0.0270 mL | 0.1349 mL | 0.2698 mL | 0.6745 mL | |
| 80 mM | 0.0202 mL | 0.1012 mL | 0.2024 mL | 0.5059 mL | |
| 100 mM | 0.0162 mL | 0.0809 mL | 0.1619 mL | 0.4047 mL |
BACE2-IN-1 関連分類
HY-136742 関連分類
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