Melineurine
Melineurine is a reversible mixed-type acetylcholinesterase inhibitor, with an IC50 of 95.3 μM against AChE and an IC50 of 28.0 μM against BChE. Melineurine is applicable to the research of Alzheimer's disease.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 85802-28-4
- 分子式: C17H17NO3
- 分子量:283.32
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Melineurine (100 μg/mL) inhibits electric eel acetylcholinesterase with an IC50 of 95.3 μM, with steric hindrance from its 3,3-dimethyl-2-propeneyloxyl substituent reducing its binding affinity compared to more potent acetylcholinesterase inhibitors[1].
Melineurine (0.1-1.0 μM, 100 μg/mL) inhibits horse serum butyrylcholinesterase with an IC50 of 28.0 μM via a mixed competitive mechanism, with strong binding affinity mediated by multiple hydrogen bonds and hydrophobic interactions with key active site residues[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 85802-28-4
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分子量 283.32
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分子式 C17H17NO3
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SMILES
COC1=C2C=COC2=NC3=C1C=CC(OC/C=C(C)/C)=C3
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Melineurine 関連分類
HY-N17394 関連分類
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