SDZ 220-040
Based on 1 Customer Validation
SDZ 220-040 is a competitive the mammalian NMDA receptor antagonist with a pKi of 8.5. SDZ 220-040 can be used in the study of neurological diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.14%
- CAS 番号: 174575-40-7
- 分子式: C16H16Cl2NO6P
- 分子量:420.18
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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NMDA Receptor 8.5 (pKi) |
SDZ 220-040 (20 μM; 9 days) induces a partially agravitropic pattern in Arabidopsis root architecture[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 174575-40-7
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性状 Solid
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分子量 420.18
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分子式 C16H16Cl2NO6P
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Color White to off-white
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SMILES
ClC1=C(C=CC(Cl)=C1)C2=CC(C[C@H](N)C(O)=O)=C(C(CP(O)(O)=O)=C2)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 50 mg/mL (119.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Brian G Forde. et al. Glutamate signalling via a MEKK1 kinase-dependent pathway induces changes in Arabidopsis root architecture. Plant J. 2013 Jul;75(1):1-10. [Content Brief]
[2]. Urwyler S, et al. Biphenyl-derivatives of 2-amino-7-phosphono-heptanoic acid, a novel class of potent competitive N-methyl-D-aspartate receptor antagonists--II. Pharmacological characterization in vivo. Neuropharmacology. 1996 Jun;35(6):655-69. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3799 mL | 11.8997 mL | 23.7993 mL | 59.4983 mL |
| 5 mM | 0.4760 mL | 2.3799 mL | 4.7599 mL | 11.8997 mL | |
| 10 mM | 0.2380 mL | 1.1900 mL | 2.3799 mL | 5.9498 mL | |
| 15 mM | 0.1587 mL | 0.7933 mL | 1.5866 mL | 3.9666 mL | |
| 20 mM | 0.1190 mL | 0.5950 mL | 1.1900 mL | 2.9749 mL | |
| 25 mM | 0.0952 mL | 0.4760 mL | 0.9520 mL | 2.3799 mL | |
| 30 mM | 0.0793 mL | 0.3967 mL | 0.7933 mL | 1.9833 mL | |
| 40 mM | 0.0595 mL | 0.2975 mL | 0.5950 mL | 1.4875 mL | |
| 50 mM | 0.0476 mL | 0.2380 mL | 0.4760 mL | 1.1900 mL | |
| 60 mM | 0.0397 mL | 0.1983 mL | 0.3967 mL | 0.9916 mL | |
| 80 mM | 0.0297 mL | 0.1487 mL | 0.2975 mL | 0.7437 mL | |
| 100 mM | 0.0238 mL | 0.1190 mL | 0.2380 mL | 0.5950 mL |
SDZ 220-040 関連分類
HY-107704 関連分類
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