NOS-IN-3
NOS-IN-3 (Compound 9a) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 4.6 μM, without inhibiting eNOS. NOS-IN-3 has little toxicity and can be studied in the research of inducible isoform involved diseases, such as septic shock.
For research use only. We do not sell to patients.
- CAS No.: 2761725-68-0
- Formula: C10H15N3O
- Molecular Weight:193.25
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
iNOS |
nNOS |
NOS-IN-3 (Compound 9a) shows high iNOS selectivity without eNOS inhibition activity [1].
NOS-IN-3 (0-100 µM, 30 min) has little toxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:HUVECs
-
Concentration:10, 20, 50, 100, 500 µM
-
Incubation Time:30 min
-
Result:Had little toxicity, only at the concentration above 100 µM, the cell viability was significantly (approximately 20%) reduced.
Chemical Information
-
CAS No. 2761725-68-0
-
Molecular Weight 193.25
-
Formula C10H15N3O
-
SMILES
CC(NCCC(C1=CC=CN=C1)O)=N
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NOS-IN-3 Related Classifications
HY-115917 Related Classifications
Powered by Bioz