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Cat. No.: HY-176439

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AChE-IN-88

AChE-IN-88 (Compound 26) is a novel pyridazine derivative. AChE-IN-88 is an orally active multi-target ligand for Alzheimer's disease (AD) that inhibits both acetylcholinesterase (AChE) and amyloid β protein (Aβ) aggregation (pIC₅₀: 7.16).

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CAS No.: 2758789-03-4
화학식: C₂₇H₃₃FN₄O₃
분자량:480.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

AChE-IN-88 Chemical Structure

CAS No.: 2758789-03-4

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수량

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

AChE

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 2758789-03-4
분자량 480.57
화학식 C₂₇H₃₃FN₄O₃
SMILES

FC1=CC(CN(CC)CCCCCCN2N=C(C3=CC(NC(C)=O)=CC=C3O)C=CC2=O)=CC=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Aloui M, et al. In silico design of novel pyridazine derivatives as balanced multifunctional agents against Alzheimer's disease. Sci Rep. 2025 May 7;15(1):15910. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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AChE-IN-88

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

AChE-IN-88 Related Classifications

HY-176439 Related Classifications