ALKBH1-IN-2
Based on 1 Customer Validation
ALKBH1-IN-2 (Compound 16) is a derivative of ALKBH1-IN-1 (HY-163385). ALKBH1-IN-2 is an ALKBH1 inhibitor. ALKBH1-IN-2 can modulate the 6mA levels.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.16%
- 화학식: C16H12F3N5O4
- 분자량:395.29
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
IC50 & Target
ALKBH1[1]
Chemical Information
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Appearance Solid
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분자량 395.29
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화학식 C16H12F3N5O4
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Color White to off-white
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SMILES
O=C(NO)C1=CN(N=C1)C2=NC=C(C=N2)OCC3=CC=CC(OC(F)(F)F)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 12.5 mg/mL (31.62 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5298 mL | 12.6489 mL | 25.2979 mL | 63.2447 mL |
| 5 mM | 0.5060 mL | 2.5298 mL | 5.0596 mL | 12.6489 mL | |
| 10 mM | 0.2530 mL | 1.2649 mL | 2.5298 mL | 6.3245 mL | |
| 15 mM | 0.1687 mL | 0.8433 mL | 1.6865 mL | 4.2163 mL | |
| 20 mM | 0.1265 mL | 0.6324 mL | 1.2649 mL | 3.1622 mL | |
| 25 mM | 0.1012 mL | 0.5060 mL | 1.0119 mL | 2.5298 mL | |
| 30 mM | 0.0843 mL | 0.4216 mL | 0.8433 mL | 2.1082 mL |