ALKBH1-IN-1
Based on 1 Customer Validation
ALKBH1-IN-1 (Compound 13h) is a selective ALKBH1 inhibitor, with an IC50 of 0.026 μM and 1.39 μM in the fluorescence polarization and enzyme activity assay, respectively. ALKBH1-IN-1 can modulate the level of DNA 6mA modifications. ALKBH1-IN-1 can be used to study the functions of ALKBH1 and DNA 6mA.
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- Pureté: 99.63%
- Formule: C16H11F3N4O4
- Masse moléculaire:380.28
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
Chemical Information
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Appearance Solid
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Masse moléculaire 380.28
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Formule C16H11F3N4O4
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Color White to off-white
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SMILES
O=C(C1=CN(C2=NC=C(OCC3=CC=CC(OC(F)(F)F)=C3)C=N2)N=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (262.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6296 mL | 13.1482 mL | 26.2964 mL | 65.7410 mL |
| 5 mM | 0.5259 mL | 2.6296 mL | 5.2593 mL | 13.1482 mL | |
| 10 mM | 0.2630 mL | 1.3148 mL | 2.6296 mL | 6.5741 mL | |
| 15 mM | 0.1753 mL | 0.8765 mL | 1.7531 mL | 4.3827 mL | |
| 20 mM | 0.1315 mL | 0.6574 mL | 1.3148 mL | 3.2871 mL | |
| 25 mM | 0.1052 mL | 0.5259 mL | 1.0519 mL | 2.6296 mL | |
| 30 mM | 0.0877 mL | 0.4383 mL | 0.8765 mL | 2.1914 mL | |
| 40 mM | 0.0657 mL | 0.3287 mL | 0.6574 mL | 1.6435 mL | |
| 50 mM | 0.0526 mL | 0.2630 mL | 0.5259 mL | 1.3148 mL | |
| 60 mM | 0.0438 mL | 0.2191 mL | 0.4383 mL | 1.0957 mL | |
| 80 mM | 0.0329 mL | 0.1644 mL | 0.3287 mL | 0.8218 mL | |
| 100 mM | 0.0263 mL | 0.1315 mL | 0.2630 mL | 0.6574 mL |