Leukotriene E3

Cat. No.: HY-171831: Data Sheet Handling Instructions
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Leukotriene E3 is a cysteinyl leukotriene metabolite derived from 5,8,11-eicosatrienoic acid (HY-108398A). Leukotriene E3 acts as a smooth-muscle-contracting mediator. Leukotriene E3 can be used for the research of allergic reactions and asthma.

For research use only. We do not sell to patients.

Leukotriene E3 Chemical Structure

CAS No. : 79494-05-6

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Description

IC₅₀ & Target^[1]

Human Endogenous Metabolite

In Vitro

Leukotriene E3 is a major in vivo metabolite of leukotriene C3 in mice, accumulating predominantly in lung tissue and persisting in kidney and blood following administration of leukotriene C3^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

441.63

Formula

C₂₃H₃₉NO₅S

CAS No.

79494-05-6

SMILES

O=C(O)CCCC(O)C(SCC(N)C(=O)O)C=CC=CC=CCCCCCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Appelgren LE, et al. Distribution and metabolism of 3H-labeled leukotriene C3 in the mouse. J Biol Chem. 1982;257(1):531-535. [Content Brief]

[2]. Hammarström S, et al. Metabolism of leukotrienes. Mol Cell Biochem. 1985 Nov;69(1):7-16. [Content Brief]

[3]. Orning L, et al. Formation of leukotrienes E3, E4 and E5 in rat basophilic leukemia cells. Eur J Biochem. 1981;120(1):41-45. [Content Brief]

Leukotriene E3 Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leukotriene E379494-05-6Leukotriene E 3Leukotriene E-3Endogenous Metaboliterat basophilic leukemia cellsrat kidneymouse lungsmooth-muscle-contracting mediatorrat liverleukotriene D3allergic reactionscysteinyl leukotriene metaboliteporcine kidney membrane-bound dipeptidase5,8,11-eicosatrienoic acidInhibitorinhibitorinhibit

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