N-Acetoxy-IQ
N-Acetoxy-IQ is a DNA alkylating agent that can covalently bind to DNA, especially guanine residues. N-Acetoxy-IQ exerts mutagenic and carcinogenic activities by forming DNA adducts. N-Acetoxy-IQ is promising for research of cancers.
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- No. CAS: 115722-78-6
- Fòrmula: C13H12N4O2
- Peso molecular:256.26
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
Chemical Information
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No. CAS 115722-78-6
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Peso molecular 256.26
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Fòrmula C13H12N4O2
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SMILES
O=C(C)O/N=C1NC2=C(N/1C)C=CC3=NC=CC=C23
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Schut HA, et al. Similar patterns of DNA adduct formation of 2-amino-3-methylimidazo [4,5-f]quinoline in the Fischer 344 rat, CDF1 mouse, cynomolgus monkey and Salmonella typhimurium. Carcinogenesis. 1991 May;12(5):931-4. [Content Brief]
[2]. Turesky RJ, et al. Formation and persistence of DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline in the rat and nonhuman primates. Mutat Res. 1997 May 12;376(1-2):235-41. [Content Brief]
[3]. Turesky RJ, et al. DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4,5- f]quinoline at the C-8 and N2 atoms of guanine. Chem Res Toxicol. 1994 Nov-Dec;7(6):752-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Acetoxy-IQ Related Classifications
HY-N15366 Related Classifications
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