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Cat. No.: HY-187019

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Nitric oxide production-IN-2

Nitric oxide production-IN-2 (compound 39) is an inhibitor of nitric oxide (NO) production. Nitric oxide production-IN-2 inhibits LPS (HY-D1056)-induced nitric oxide production in RAW 264.7 cells, and it can be used in studies related to inflammation and nitric oxide production.

For research use only. We do not sell to patients.

CAS No.: 2418576-62-0
Formula: C₁₉H₂₀O₅
Molecular Weight:328.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nitric oxide production-IN-2 Chemical Structure

CAS No.: 2418576-62-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

All NO Synthase Isoforms :

In Vitro

Nitric oxide production-IN-2 (compound 39) (10 μM; 24 h) inhibits NO production in LPS-induced RAW 264.7 macrophages, showing a 46.4% inhibitory rate at 10 µM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2418576-62-0
Molecular Weight 328.36
Formula C₁₉H₂₀O₅
SMILES

C(/C(=C/C1=CC=C(OC)C=C1)/C)(=O)C2=C(OC)C=C(OC)C=C2O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yang Y, et al. Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation. European Journal of Medicinal Chemistry. 2020;193:112216. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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Nitric oxide production-IN-2

All NO Synthase Isoforms