- Click Chemistry
- DBCO
DBCO
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DBCO (309)
- Formula: C41H56N2O14
- Molecular Weight: 800.89
DBCO-N-bis(PEG4-acid) is a branched click chemistry reagent. The DBCO group enables copper-free Click Chemistry reactions. carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or HATU to form a stable amide bond.
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- Formula: C38H53N3O10
- Molecular Weight: 711.84
DBCO-PEG6-NH-Boc is a click chemistry reagent with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound.
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- Formula: C50H66N6O13
- Molecular Weight: 959.09
Methyltetrazine-PEG11-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.
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- Formula: C46H45N9O10S
- Molecular Weight: 915.97
Sulfo DBCO-UBQ-2 is a click chemistry reagent combining a dark quencher, UBQ-2, with a polyaromatic-azo backbone, offering no native emission. UBQ-2 effectively quenches fluorescence in the 560-670 nm range, ideal for qPCR probes and FRET applications with orange to far-red dyes.
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- Formula: C53H48N4O11S2
- Molecular Weight: 981.10
AF594 DBCO is an AlexaFluor 594-conjugated DBCO click chemistry probe for fluorescent labeling of azido-modified cholesterol probes. DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection.
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- Formula: C84H101N7O21S
- Molecular Weight: 1576.80
ICG-DBCO-1-Maltotriose is a specific imaging agent for detecting bacterial infections. ICG-DBCO-1-Maltotriose is composed of the fluorescent dye Indocyanine green (ICG) (HY-D0711) and a maltotriose sugar.
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- Formula: C53H46K3N3O13S4
- Molecular Weight: 1178.50
Sulfo-Cy3.5-DBCO is a fluorescent dye. Sulfo-Cy3.5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C63H62N4Na2O11S3
- Molecular Weight: 1193.36
Disulfo-ICG-DBCO disodium is a double sulfonic acid-modified indocyanine green. Disulfo-ICG-DBCO disodium can react with d-AzAla modified bacteria to detect the bacteria by copper-free click chemistry-mediated photothermal lysis and measurement of ATP bioluminescence.
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- Formula: C28H20F4N2O7S
- Molecular Weight: 604.53
Sulfo DBCO-TFP Ester is a water-soluble, sulfo-containing click chemistry reagent. Sulfo DBCO-TFP Ester enables simple and efficient incorporation of sulfo-DBCO moieties onto amine-containing molecules.
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