p38α inhibitor 5
Based on 1 Customer Validation
p38α inhibitor 5 (compound 1) is a PROTAC-type target protein ligand targeting p38 and can be used to synthesize NR-11c (HY-159798).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.69%
- No. CAS: 2550397-96-9
- Fòrmula: C26H23BrF2N2O3
- Peso molecular:529.37
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
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p38α |
Chemical Information
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No. CAS 2550397-96-9
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Appearance Solid
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Peso molecular 529.37
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Fòrmula C26H23BrF2N2O3
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Color Light yellow to yellow
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SMILES
CC(C(N1C(C)=CC(OCC2=CC=C(C=C2F)F)=C(C1=O)Br)=C3)=CC=C3C(NCCCC#C)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (188.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8890 mL | 9.4452 mL | 18.8904 mL | 47.2259 mL |
| 5 mM | 0.3778 mL | 1.8890 mL | 3.7781 mL | 9.4452 mL | |
| 10 mM | 0.1889 mL | 0.9445 mL | 1.8890 mL | 4.7226 mL | |
| 15 mM | 0.1259 mL | 0.6297 mL | 1.2594 mL | 3.1484 mL | |
| 20 mM | 0.0945 mL | 0.4723 mL | 0.9445 mL | 2.3613 mL | |
| 25 mM | 0.0756 mL | 0.3778 mL | 0.7556 mL | 1.8890 mL | |
| 30 mM | 0.0630 mL | 0.3148 mL | 0.6297 mL | 1.5742 mL | |
| 40 mM | 0.0472 mL | 0.2361 mL | 0.4723 mL | 1.1806 mL | |
| 50 mM | 0.0378 mL | 0.1889 mL | 0.3778 mL | 0.9445 mL | |
| 60 mM | 0.0315 mL | 0.1574 mL | 0.3148 mL | 0.7871 mL | |
| 80 mM | 0.0236 mL | 0.1181 mL | 0.2361 mL | 0.5903 mL | |
| 100 mM | 0.0189 mL | 0.0945 mL | 0.1889 mL | 0.4723 mL |
p38α inhibitor 5 Related Classifications
HY-159799 Related Classifications
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