1. Cell Cycle/DNA Damage
  2. IRE1
  3. PAIR2

PAIR2 

Cat. No.: HY-145425
Handling Instructions

PAIR2 is a potent and selective partial antagonist of IRE1α RNase. PAIR2 can completely occupy IRE1α’s ATP-binding site in cells and block the ability of a potent KIRA to inhibit XBP1 splicing.

For research use only. We do not sell to patients.

PAIR2 Chemical Structure

PAIR2 Chemical Structure

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Description

PAIR2 is a potent and selective partial antagonist of IRE1α RNase. PAIR2 can completely occupy IRE1α’s ATP-binding site in cells and block the ability of a potent KIRA to inhibit XBP1 splicing[1].

Molecular Weight

590.59

Formula

C27H26F4N6O3S

SMILES

CC(C(F)=C(NS(CC(F)(F)F)(=O)=O)C1=C2C=CC=C1)=C2OC3=NC=CC=C3C4=NC(N[[email protected]]5CCCNC5)=NC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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This equation is commonly abbreviated as: C1V1 = C2V2

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PAIR2
Cat. No.:
HY-145425
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