2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S,R,S)-AHPC-Me-C10-Br

(S,R,S)-AHPC-Me-C10-Br 

Cat. No.: HY-130642 Purity: 97.21%
COA Handling Instructions

(S,R,S)-AHPC-Me-C10-Br is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-C10-Br incorporates a VHL E3 ligase linker and MS432 based on the MEK1/2 inhibitor PD0325901.

For research use only. We do not sell to patients.

(S,R,S)-AHPC-Me-C10-Br Chemical Structure

(S,R,S)-AHPC-Me-C10-Br Chemical Structure

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50 mg USD 600 In-stock
100 mg USD 900 In-stock
250 mg USD 1700 In-stock
500 mg   Get quote  
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Based on 1 publication(s) in Google Scholar

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1

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Description

(S,R,S)-AHPC-Me-C10-Br is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-C10-Br incorporates a VHL E3 ligase linker and MS432 based on the MEK1/2 inhibitor PD0325901[1].

IC50 & Target[1]

VHL

 

Molecular Weight

691.76

Appearance

Solid

Formula

C34H51BrN4O4S
SMILES

O=C(N[[email protected]@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[[email protected]]3N(C[[email protected]@H](C3)O)C([[email protected]@H](NC(CCCCCCCCCCBr)=O)C(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

(S,R,S)-AHPC-Me-C10-BrE3 Ligase Ligand-Linker Conjugatesligand-linkerconjugateInhibitorinhibitorinhibit

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