(S,R,S)-AHPC-Me-C10-Br
Based on 1 Customer Validation
(S,R,S)-AHPC-Me-C10-Br is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-C10-Br incorporates a VHL E3 ligase linker and MS432 based on the MEK1/2 inhibitor PD0325901.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 2836297-55-1
- Formula: C34H51BrN4O4S
- Molecular Weight:691.76
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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VHL |
Chemical Information
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CAS No. 2836297-55-1
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Appearance Solid
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Molecular Weight 691.76
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Formula C34H51BrN4O4S
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Color White to off-white
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SMILES
O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(CCCCCCCCCCBr)=O)C(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (144.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4456 mL | 7.2279 mL | 14.4559 mL | 36.1397 mL |
| 5 mM | 0.2891 mL | 1.4456 mL | 2.8912 mL | 7.2279 mL | |
| 10 mM | 0.1446 mL | 0.7228 mL | 1.4456 mL | 3.6140 mL | |
| 15 mM | 0.0964 mL | 0.4819 mL | 0.9637 mL | 2.4093 mL | |
| 20 mM | 0.0723 mL | 0.3614 mL | 0.7228 mL | 1.8070 mL | |
| 25 mM | 0.0578 mL | 0.2891 mL | 0.5782 mL | 1.4456 mL | |
| 30 mM | 0.0482 mL | 0.2409 mL | 0.4819 mL | 1.2047 mL | |
| 40 mM | 0.0361 mL | 0.1807 mL | 0.3614 mL | 0.9035 mL | |
| 50 mM | 0.0289 mL | 0.1446 mL | 0.2891 mL | 0.7228 mL | |
| 60 mM | 0.0241 mL | 0.1205 mL | 0.2409 mL | 0.6023 mL | |
| 80 mM | 0.0181 mL | 0.0903 mL | 0.1807 mL | 0.4517 mL | |
| 100 mM | 0.0145 mL | 0.0723 mL | 0.1446 mL | 0.3614 mL |
(S,R,S)-AHPC-Me-C10-Br Related Classifications
HY-130642 Related Classifications
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