2. MAPK/ERK Pathway
  3. p38 MAPK
  4. SB 202474

SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction.

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SB 202474

SB 202474 Chemical Structure

CAS No. : 172747-50-1

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Based on 1 publication(s) in Google Scholar

SB 202474 Related Antibodies

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1 Publications Citing Use of MCE SB 202474

Voir tous les produits spécifiques à Isoform p38 MAPK:

Voir toutes les isoformes
p38 MAPK Akt1 p38α p38β MAPK13 p38δ p38γ

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Description

SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction[1].

Masse moléculaire

279.34

Formule

C17H17N3O
CAS No.
Appearance

Solid

Color

Off-white to pink

SMILES

COC1=CC=C(C2=NC(CC)=C(C3=CC=NC=C3)N2)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Pureté et documentation
Références
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SB 202474 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB 202474172747-50-1SB202474SB-202474p38 MAPKnegativeanalogmelaninsynthesisinductionInhibitorinhibitorinhibit

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