2. MAPK/ERK Pathway
  3. p38 MAPK
  4. EO 1428

EO 1428 is a highly specific inhibitor of p38 of the aminobenzophenone class. EO 1428 (1 μM ) markedly attenuates LPS-induced tumor necrosis factor α-converting enzyme (TACE) activity up-regulation.

For research use only. We do not sell to patients.

EO 1428 Chemical Structure

EO 1428 Chemical Structure

CAS No. : 321351-00-2

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EO 1428 Related Antibodies

Top Publications Citing Use of Products

View All p38 MAPK Isoform Specific Products:

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

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Description

EO 1428 is a highly specific inhibitor of p38 of the aminobenzophenone class. EO 1428 (1 μM ) markedly attenuates LPS-induced tumor necrosis factor α-converting enzyme (TACE) activity up-regulation[1].

Molecular Weight

415.71

Formula

C20H16BrClN2O
CAS No.
SMILES

O=C(C1=CC=C(NC2=CC=C(Br)C=C2N)C=C1Cl)C3=CC=CC=C3C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EO 1428 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EO 1428321351-00-2EO1428EO-1428p38 MAPKspecific p38 inhibitortumor necrosis factor α-converting enzymeTACEInhibitorinhibitorinhibit

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