197 Results for "

AI

" in MedChemExpress (MCE) Product Catalog:
Products (197)

197 Results for "AI" in MCE Product Catalog:

Cat. No.: HY-P10551
ApoA-I mimetic peptide 5A is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). ApoA-I mimetic peptide 5A can promote the efflux of cholesterol from cells and help reduce the accumulation of cholesterol in cells. ApoA-I mimetic peptide 5A also shows anti-inflammatory activity and can reduce inflammatory markers in blood and tissues. ApoA-I mimetic peptide 5A can be used in the study of cardiovascular diseases .
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Cat. No.: HY-124834
CAS No.: 75483-04-4
Target:  

Keap1-Nrf2 Apoptosis

Research Areas:  

Cancer

Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.
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Cat. No.: HY-P6365B
CAS No.: 452782-06-8
Synonyms: D-4F
Target:  

Apolipoprotein

Research Areas:  

Cardiovascular Disease

APP-018 (D-4F) is 18 D-amino acids peptide that mimics apolipoprotein A-I (apoA-I). APP-018 improves the anti-inflammatory activity of high-density lipoprotein (HDL). APP-018 can be used in researches of cardiovascular diseases .
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Cat. No.: HY-113066S1
Synonyms: GDP-13C10 dilithium
Guanosine 5'-diphosphate- 13C10 (GDP- 13C10) dilithium is 13C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
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Cat. No.: HY-P6365
Synonyms: L-4F TFA
Target:  

Apolipoprotein

Research Areas:  

Cardiovascular Disease

APL180 TFA (L-4F) is an apolipoprotein AI mimetic peptide that enhances the anti-inflammatory activity of high-density lipoprotein (HDL). APL180 can be used in the study of cardiovascular diseases.
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Cat. No.: HY-113066S
Purity:  98.20%
Synonyms: GDP-15N5 dilithium
Guanosine 5'-diphosphate- 15N5 (GDP- 15N5) dilithium is 15N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .
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Cat. No.: HY-113066AR
CAS No.: 7415-69-2
Synonyms: GDP disodium salt (Standard)
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
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Cat. No.: HY-117005
CAS No.: 1036730-46-7
Purity:  ≥97.0%
Target:  

Bacterial

Research Areas:  

Infection

C450-0730 is an antagonist targeting the AHL membrane-bound sensor kinase and is an antagonist of the nine-transmembrane protein LuxN of Vibrio harveyi . C450-0730 competitively binds to the LuxN AI-1 binding site and specifically antagonizes the LuxN/AI-1 quorum sensing signal in Vibrio harveyi. The inhibitory activity of C450-0730 against LuxN I209F was not significant .
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Cat. No.: HY-175641
CAS No.: 3050609-32-7
Target:  

HPPD

Research Areas:  

Others

HPPD-IN-6 (Compound IIy) is a HPPD inhibitor with high rice selectivity. HPPD-IN-6 has potent herbicidal activities against Echinochloa crus-galli and Leymus chinensis, including the herbicide-resistant biotypes with EC50s of 19.62-33.26 g of ai/ha. HPPD-IN-6 effectively controls the weeds in rice fields at 90-150 g of ai/ha. HPPD-IN-6 can be used for the development of herbicide .
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Cat. No.: HY-113510
CAS No.: 89886-42-0
9(S)-HOTrE is a PPARα activator and an inducer of apolipoprotein A-I (apoA-I) mRNA expression. 9(S)-HOTrE upregulates the expression of PPARα target gene CPT1α. 9(S)-HOTrE can be used in the research of cardiovascular diseases .
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Cat. No.: HY-W012927
CAS No.: 19322-27-1
Synonyms: Chicory furaneol
Research Areas:  

Others

4-Hydroxy-5-methylfuran-3 (2H)-one (Chicory furaneol) is a mimic of bacterial quorum-sensing autoinducer AI-2. 4-Hydroxy-5-methylfuran-3 (2H)-one is produced by the yeast Saccharomyces cerevisiae, can be recognized by the AI-2 receptor LuxP of Vibrio harveyi and activate the AI-2-associated quorum-sensing signaling pathway, and is used for studying cross-species chemical communication and quorum-sensing mechanisms .
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Cat. No.: HY-W590664
CAS No.: 13031-64-6
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

C2 Dihydroceramide is a derivative of C2 Ceramide (HY-101180). C2 Dihydroceramide enhances the ABCA1-mediated cholesterol efflux to apolipoprotein A-I (apoA-I) without causing cytotoxicity .
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Cat. No.: HY-145360
CAS No.: 2100133-77-3
Research Areas:  

Cancer

eIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-6 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) .
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Cat. No.: HY-125966
CAS No.: 63053-14-5
Target:  

RUNX

Research Areas:  

Cancer

AI-4-57 is an allosteric inhibitor for CBFβ SMMHC-RUNX1 (core binding factor β and the smooth-muscle myosin heavy chain) interaction with an IC50 of 22 μM .
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Cat. No.: HY-P6365A
CAS No.: 388566-97-0
Synonyms: L-4F
Target:  

Apolipoprotein

Research Areas:  

Cardiovascular Disease

APL180 (L-4F) is an apolipoprotein A-I mimic peptide, that improves the anti-inflammatory activity of high-density lipoprotein (HDL). APL180 can be used in researches of cardiovascular diseases .
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Cat. No.: HY-179286
CAS No.: 3070057-48-3
Target:  

Herbicide

Research Areas:  

Others

DHAD-IN-2 (compound 6ag) is a potent dihydroxy acid dehydratase (DHAD) inhibitor with a KD of 20 μM. DHAD-IN-2 demonstrates over 85% control effectiveness against Eclipta prostrata, Amaranthus retroflexus, and Setaria viridis at a dosage of 150 g ai/ha, while also showing safety for rice. DHAD-IN-2 can be used for herbicide research .
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Cat. No.: HY-107736
CAS No.: 882288-28-0
AI-3 is a potent ARE (antioxidant response element) activator. AI-3 increases the NQO1 at the transcript levels and protein expression levels. AI-3 has the potential for the research of oxidative stress related diseases .
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Cat. No.: HY-168914
Target:  

Dengue Virus

Research Areas:  

Infection

A181 (AI-181) is a DENV-2 inhibitor. A181 can be used for anti-dengue studies .
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Cat. No.: HY-167244
CAS No.: 5823-25-6
Target:  

Insecticide

Research Areas:  

Others

AI 3-23445 is a compound with environmental toxicity and insecticidal activity, capable of inducing avoidance behavior in Peromyscus maniculatus and Mus musculus. AI 3-23445 can be utilized in agricultural research .
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Cat. No.: HY-R01642
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-548ai mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
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