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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
69 Results for "
Cryptococcus neoformans
" in MedChemExpress (MCE) Product Catalog:
Products (69)
69 Results for "Cryptococcus neoformans" in MCE Product Catalog:
製品番号: HY-W716339
CAS 番号: 19902-08-0
別名: d-β-Pinene
Target:
製品番号: HY-19404
CAS 番号: 329744-44-7
別名: CS-758; R-120758
Embeconazole (CS-758; R-120758) is an antifungal agent against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Aspergillus flavus, with MICs of 8, 16, 63 and 250 μM, respectively .
製品番号: HY-173428
Antifungal agent 130 (Compound A7) is an orally active antifungal agent. Antifungal agent 130 has good antifungal activity against Candida albicans (MIC = 0.12 ng/mL) and Cryptococcus neoformans (MIC = 0.12 ng/mL) and has excellent antivirulence effect. Antifungal agent 130 exerts its antifungal effect by disrupting the iron homeostasis of fungal cells and inducing oxidative stress damage. Antifungal agent 130 can inhibit the formation of fungal virulence factors (such as biofilm, capsule, urease and melanin). Antifungal agent 130 has good antifungal effect and can be used in the study of drug-resistant fungal infections .
製品番号: HY-P10410
CAS 番号: 2035042-31-8
製品番号: HY-P5569
CAS 番号: 865714-65-4
製品番号: HY-161049
CAS 番号: 3036399-40-0
Antifungal agent 89 (compound 28) is a antifungal agent against Cryptococcus neoformans with minimum inhibitory concentration value ranging from 0.8 to 52.17 μM .
製品番号: HY-118847
CAS 番号: 327077-97-4
Antifungal agent 86 (Compound 41F5) is an antifungal agent. Antifungal agent 86 is highly active
against Histoplasma yeast and Cryptococcus neoformans (MIC50: 0.4-0.8 μM) .
製品番号: HY-152896
CAS 番号: 897386-27-5
Category:
Target:
製品番号: HY-181101
CAS 番号: 3097563-43-1
Antifungal agent 151 is a Prp8 intein inhibitor that inhibits the self-splicing process of the Prp8 intein, preventing maturation of the Prp8 protein. Antifungal agent 151 exerts in vitro antifungal activity against Cryptococcus neoformans and Cryptococcus gattii. Antifungal agent 151 can be used for the research of cryptococcus pneumonia .
製品番号: HY-N16051
CAS 番号: 399509-71-8
別名: CJ-19784
製品番号: HY-144632
CAS 番号: 2640054-39-1
Antifungal agent 22 (compound D16) is a potential and orally active antifungal agent for CM (cryptococcal meningitis), with an IC50 of 0.5 μg/mL. Antifungal agent 22 can penetrate the blood-brain barrier and kill the C. neoformans H99 cells by destroying the integrity of fungal cell membranes. Antifungal agent 22 shows selective anti-Cryptococcus activity with good metabolic stability and low cytotoxicity .
製品番号: HY-124384
CAS 番号: 1159392-22-9
別名: Soudanone A
Category:
Target:
Phosphomannose isomerase is the first enzyme involved in the biosynthesis pathway of GDP-Man. Phosphomannose isomerase catalyzes the conversion between fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P). Phosphomannose isomerase is important for cell wall synthesis and protein glycosylation. Phosphomannose isomerase is a potent antifungal target to curb the threats posed by A. flavus .
製品番号: HY-117092
CAS 番号: 158054-02-5
Target:
研究分野:
BE-31405 is an antifungal antibiotic. BE-31405 can be isolated from the culture broth of the fungal strains such as Penicillium minioluteum F31405, Talaromyces siamensis FKA-61, and Phomopsis sp. FKA-62. BE-31405 exhibits potent growth inhibitory activity against pathogenic fungal strains including Candida albicans, Candida glabrata, and Cryptococcus neoformans. BE-31405 shows no cytotoxicity against mammalian cells .
製品番号: HY-N19644
CAS 番号: 884604-98-2
Category:
Target:
製品番号: HY-181784
Ac-CoA-IN-1 is an acyl-AMP phosphate analog and weak inhibitor of Candida albicans acetyl-CoA synthetase 2, with no activity against Cryptococcus neoformans acetyl-CoA synthetase 1. Ac-CoA-IN-1 crystallizes with Cryptococcus neoformans ACS1 enzyme to yield structural insight for inhibitor design. Ac-CoA-IN-1 can be used for the research of fungal infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
