(+)-β-Pinene
(+)-β-Pinene (d-β-Pinene) acts as an Antifungal and Antibacterial agent. (+)-β-Pinene inhibits Phospholipase. (+)-β-Pinene interferes with fungal cell wall function, reduces Candida biofilm adhesion, inhibits Candida albicans biofilm formation, and suppresses the growth of various Candida species. Combined with Ciprofloxacin (HY-B0356), (+)-β-Pinene exerts synergistic antibacterial activity against Methicillin (HY-121544)-resistant Staphylococcus aureus. (+)-β-Pinene can be used in research related to candidiasis and Staphylococcus aureus infections.
For research use only. We do not sell to patients.
- CAS No.: 19902-08-0
- Formula: C10H16
- Molecular Weight:136.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
(+)-β-Pinene exhibits antifungal and anti-biofilm activity against 25 reference and clinical Candida spp. strains (including antifungal-susceptible and resistant isolates) with MIC values ranging from <56.25 to 1800 µmol/L, and acts primarily via cell wall interference rather than ergosterol binding[1].
(+)-β-Pinene exhibits microbicidal activity against Candida albicans ATCC 10231, Cryptococcus neoformans T1-444, Rhizopus oryzae UCP1506, and MRSA BMB9393 with MIC values of 187 µg/mL, 234 µg/mL, 780 µg/mL, and 6250 µg/mL, respectively[2].
(+)-β-Pinene (5 min-6 h) kills 100% of Candida albicans ATCC 10231 within 60 min and 100% of MRSA BMB9393 within 6 h when used at its respective MIC concentration[2].
(+)-β-Pinene (93.5-3125 µg/mL; 24 h) inhibits phospholipase activity by up to 37.91% and esterase activity by up to 72.6% in Cryptococcus neoformans T1-444, with minimal inhibition in Candida albicans ATCC 10231 and MRSA BMB9393[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 19902-08-0
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Molecular Weight 136.23
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Formula C10H16
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SMILES
CC1([C@@H]2C[C@H]1CCC2=C)C
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Synonyms
d-β-Pinene
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. de Macêdo Andrade AC, et al. Antifungal Activity, Mode of Action, Docking Prediction and Anti-biofilm Effects of (+)-β-pinene Enantiomers against Candida spp. Current topics in medicinal chemistry. 2018;18(29):2481-2490. [Content Brief]
[2]. Rivas da Silva AC, et al. Biological activities of α-pinene and β-pinene enantiomers. Molecules (Basel, Switzerland). 2012 May 25;17(6):6305-16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(+)-β-Pinene Related Classifications
HY-W716339 Related Classifications
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