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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
47 Results for "
Ina
" in MedChemExpress (MCE) Product Catalog:
Products (47)
47 Results for "Ina" in MCE Product Catalog:
Art. -Nr.: HY-B0280S
CAS. Nr.: 1092804-87-9
Synonyms: CVT 303-d5; RS 43285-003-d5
Art. -Nr.: HY-RS06802
Target:
Forschungsgebiete:
INA Human Pre-designed siRNA Set A contains three designed siRNAs for INA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS16782
Target:
Forschungsgebiete:
Ina Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ina gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-12593R
CAS. Nr.: 1262618-39-2
Target:
Forschungsgebiete:
GS967 (Standard) is the analytical standard of GS967. This product is intended for research and analytical applications. GS967 (GS-458967) is a potent, and selective inhibitor of cardiac late sodium current (late INa ) with IC50 values of 0.13 and 0.21 μM for ventricular myocytes and isolated hearts, respectively.
Art. -Nr.: HY-156976
CAS. Nr.: 343935-60-4
Target:
Forschungsgebiete:
Sulcardine is a multi-ion channel blocker that can reduce INa and ICa with IC50 values of 26.9 µM and 69.2 µM, respectively. Sulcardine is a potent hNav1.5 channel blocker with a mild inhibitory effect on hERG channels. Sulcardine has anti-arrhythmic effects .
Art. -Nr.: HY-156976A
CAS. Nr.: 343935-48-8
Target:
Forschungsgebiete:
Sulcardine hydrochloride is a multi-ion channel blocker that can reduce INa and ICa with IC50 values of 26.9 µM and 69.2 µM, respectively. Sulcardine hydrochloride is a potent hNav1.5 channel blocker with a mild inhibitory effect on hERG channels. Sulcardine hydrochloride has anti-arrhythmic effects .
Art. -Nr.: HY-111245
CAS. Nr.: 872045-91-5
Forschungsgebiete:
AZD-1305 is an antiarrhythmic agent and atrial selective sodium channel/potassium channel blocker, which can significantly prolongs action potential duration and reduces excitability, cause atrial selective ERP prolongation and acute termination of atrial fibrillation. AZD1305 can be used for atrial fibrillation research .
Art. -Nr.: HY-126005
CAS. Nr.: 2230472-55-4
Target:
Forschungsgebiete:
VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5). VGSC blocker-1 blocks INa peak currents 34.9% at 1 μM and inhibits cell invasion 0.3% at 1 μM in human breast cancer cell line MDA-MB-231, without affecting the cell viability .
Art. -Nr.: HY-B0280R
CAS. Nr.: 95635-55-5
Synonyms: CVT 303 (Standard); RS 43285-003 (Standard)
Forschungsgebiete:
Ranolazine (Standard) is the analytical standard of Ranolazine. This product is intended for research and analytical applications. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) . Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor . Antianginal agent.
Target:
Indoleamine 2,3-Dioxygenase (IDO) Calcium Channel Sodium Channel Potassium Channel Cytochrome P450
Forschungsgebiete:
IDO1-IN-19 (Compound 17) is an orally active IDO1 inhibitor with an IC50 of CYP2C9 of 8.64 μM. IDO1-IN-19 also acts funciton on cardiac channels, with IC50s of 12 μM (IKr), 40 μM (INa), 8.3 μM (ICa), respectively. IDO1-IN-19 has the potential to study cancer diseases .
Art. -Nr.: HY-18600AS
Synonyms: NE-10064-d8 dihydrochloride
Art. -Nr.: HY-P992387
Target:
Forschungsgebiete:
Art. -Nr.: HY-RS23222
Target:
Forschungsgebiete:
Ina Rat Pre-designed siRNA Set A contains three designed siRNAs for Ina gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P88426A
Synonyms: AHUS3; ARMD13; C3b-Ina; C3BIna; FI; IF; KAF
Art. -Nr.: HY-A0236AR
CAS. Nr.: 33237-74-0
Forschungsgebiete:
Aprindine hydrochloride (Standard) is the analytical reference standard of Aprindine hydrochloride (HY-A0236A). This product is used for research and analytical applications. Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. Aprindine hydrochloride mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine hydrochloride significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine hydrochloride can also regulate intracellular calcium ion concentration by inhibiting Na +/Ca 2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine hydrochloride can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
