1262618-39-2
1262618-39-2
Chemical Structure
GS967
- CAS No.: 1262618-39-2
- Formula:C14H7F6N3O
- Molecular Weight:347.22
IUPAC Name: 6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
InChIKey: FEVBKJITJDHASC-UHFFFAOYSA-N
SMILES: FC(C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21)(F)F
Biological Activity: GS967 (GS-458967) is a potent, and selective inhibitor of cardiac late sodium current (late INa ) with IC50 values of 0.13 and 0.21 μM for ventricular myocytes and isolated hearts, respectively.
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GS967 | 99.55% | GS967 (GS-458967) is a potent, and selective inhibitor of cardiac late sodium current (late INa ) with IC50 values of 0.13 and 0.21 μM for ventricular myocytes and isolated hearts, respectively. | ||||||||||||||||||||
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GS967 (Standard) | ≥98% | GS967 (Standard) is the analytical standard of GS967. This product is intended for research and analytical applications. GS967 (GS-458967) is a potent, and selective inhibitor of cardiac late sodium current (late INa ) with IC50 values of 0.13 and 0.21 μM for ventricular myocytes and isolated hearts, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.58
HY-179573UCM-A86 -
Similarity Score 0.57
HY-117229Sonidegib metabolite M48 -
Similarity Score 0.57
HY-159819Vormatrigine -
Similarity Score 0.57
HY-174976FHND5032 -
Similarity Score 0.56
HY-110325PF-04885614 -
Similarity Score 0.56
HY-138617AI-10-47 -
Similarity Score 0.56
HY-103505RCL 218872 (Standard) -
Similarity Score 0.56
HY-175003HV1-IN-2 -
Similarity Score 0.55
HY-W1120964,4'-(2-(Trifluoromethyl)-1,4-phenylene)dipyridine -
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