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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
KDM6
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "KDM6" in MCE Product Catalog:
Cat. No.: HY-15648I
CAS No.: 2108665-15-0
Target:
Research Areas:
GSK-J2 sodium is the sodium form of GSK-J2 (HY-15648A). GSK-J2 is an isomer of GSK-J1, and does not have any specific activity. GSK-J1 (HY-15648) is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A .
Cat. No.: HY-N6896R
CAS No.: 40788-84-9
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants
Cat. No.: HY-RS16705
Target:
Research Areas:
Kdm6a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kdm6a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23140
Target:
Research Areas:
Kdm6a Rat Pre-designed siRNA Set A contains three designed siRNAs for Kdm6a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23655
Target:
Research Areas:
Kdm6b Rat Pre-designed siRNA Set A contains three designed siRNAs for Kdm6b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-100764R
CAS No.: 708991-09-7
Research Areas:
YUKA1 (Standard) is the analytical standard of YUKA1 (HY-100764). This product is intended for research and analytical applications. YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 μM. YUKA1 has less inhibitory active on KDM5C (IC50 = 7.12 μM) and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 can increase H3K4me3 levels and inhibit cell proliferation. YUKA1 can be used for the research of cancer, such as lung and breast cancers .
Cat. No.: HY-P702082
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDM6B; Lysine (K)-Specific Demethylase 6B; Prev. JMJD3; Lysine-Specific Demethylase 6B; KIAA0346; [Histone H3]-Trimethyl-L-Lysine(27) Demethylase; Jumonji Domain Containing 3, Histone Lysine Demethylase; Jumonji Domain Containing 3; [Histone H3]-Trimethyl
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702083
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM6B; Lysine (K)-Specific Demethylase 6B; Prev. JMJD3; Lysine-Specific Demethylase 6B; KIAA0346; [Histone H3]-Trimethyl-L-Lysine(27) Demethylase; Jumonji Domain Containing 3, Histone Lysine Demethylase; Jumonji Domain Containing 3; [Histone H3]-Trimethyl
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P811304
Synonyms: JMJD3, KIAA0346, KDM6B, Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Lysine demethylase 6B, [histone H3]-trimethyl-L-lysine(27) demethylase 6B
Cat. No.: HY-183618
Target:
Research Areas:
DW-229 is a PROTAC degrader derived from Deferiprone (HY-B0568), targeting Fe(II)/α‑ketoglutarate‑dependent histone lysine demethylases (KDMs). DW-229 degrades KDM2A, KDM3A, KDM5B, KDM4A‑C, KDM5C, KDM6B in breast cancer cells. DW-229 shows IC50 < 0.5 μM against MCF‑7 cells and IC50 of 8.87 μM against MDA‑MB‑231 cells, with high cancer cell selectivity. DW-229 can be used for the research of breast cancer, liver cancer, prostate cancer, lung cancer .
Cat. No.: HY-138794G
CAS No.: 2417089-74-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
