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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
MLK
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "MLK" in MCE Product Catalog:
Cat. No.: HY-RS17455
Target:
Research Areas:
Musk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Musk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702929
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K11; Src-Homology 3 Domain-Containing Proline-Rich Kinase; Prev. MLK3; SH3 Domain-Containing Proline-Rich Kinase; Prev. PTK1; Protein-Tyrosine Kinase PTK1; SPRK; MLK-3; MEKK11; Mitogen-Activated Protein Kinase Kinase Kinase 11; Mixed Lineage Kinase 3
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P83492A
Synonyms: MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
Cat. No.: HY-P703370
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K21; KIAA1804; Mitogen-Activated Protein Kinase Kinase Kinase 21; Mitogen-Activated Protein Kinase Kinase Kinase MLK4; MLK4; DJ862P8.3; Mixed Lineage Kinase 4
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705606
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K10; MEKK10; Prev. MLK2; Protein Kinase MST; MST; MKN28 Kinase; Mixed Lineage Kinase 2; Mitogen-Activated Protein Kinase Kinase Kinase 10; MKN28 Derived Nonreceptor_type Serine/Threonine Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706067
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K10; MEKK10; Prev. MLK2; Protein Kinase MST; MST; MKN28 Kinase; Mixed Lineage Kinase 2; Mitogen-Activated Protein Kinase Kinase Kinase 10; MKN28 Derived Nonreceptor_type Serine/Threonine Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705605
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K9; MEKK9; Prev. MLK1; Mitogen-Activated Protein Kinase Kinase Kinase; PRKE1; Mixed Lineage Kinase 1; Mitogen-Activated Protein Kinase Kinase Kinase 9; Mixed Lineage Kinase 1 (Tyr And Ser/Thr Specificity)
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705995
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K9; MEKK9; Prev. MLK1; Mitogen-Activated Protein Kinase Kinase Kinase; PRKE1; Mixed Lineage Kinase 1; Mitogen-Activated Protein Kinase Kinase Kinase 9; Mixed Lineage Kinase 1 (Tyr And Ser/Thr Specificity)
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P810809
Synonyms: LZK, MAP3K13, Mitogen-activated protein kinase kinase kinase 13, Leucine zipper-bearing kinase, Mixed lineage kinase, MLK
Cat. No.: HY-184396
Research Areas:
GR2-128 is a dual inhibitor targeting MLK3 and NAMPT with IC50 values of 84 nM and 14 nM, respectively. GR2-128 inhibits downstream JNK/c‑Jun signaling and reduces NAD + levels. GR2-128 exhibits antiproliferative and pro-apoptotic activities in triple-negative breast cancer cells without significant toxicity to normal cells. GR2-128 suppresses tumor growth, reduces macrophage and neutrophil infiltration, and increases tumor T-cell markers in a syngeneic mouse model, and can be used for triple-negative breast cancer research .
Cat. No.: HY-147141A
Research Areas:
HS-276 hydrochloride is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 hydrochloride shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 hydrochloride reduces the expression of TNF, IL-6, and IL-1β. HS-276 hydrochloride can be used for rheumatoid arthritis (RA) research .
Cat. No.: HY-147141B
Research Areas:
HS-276 formic is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 formic shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 formic reduces the expression of TNF, IL-6, and IL-1β. HS-276 formic can be used for rheumatoid arthritis (RA) research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
