Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
PCAF
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "PCAF" in MCE Product Catalog:
Cat. No.: HY-107569R
CAS No.: 78824-30-3
Category:
Cat. No.: HY-N2020R
CAS No.: 16611-84-0
Synonyms: Hydroginkgolic acid (Standard); Ginkgolic Acid C15:0 (Standard)
Cat. No.: HY-146277
CAS No.: 2592638-13-4
Target:
Research Areas:
CBP/p300-IN-19 is a potent p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively. CBP/p300-IN-19 shows antitumor activity .
Target:
Research Areas:
CBP/p300-IN-19 hydrochloride is a potent and selective p300/CBP HAT inhibitor with IC50s of 1.4, 2.2, >100, >100 µM for p300-HAT, CBP-HAT, PCAF, Myst3, respectively. CBP/p300-IN-19 hydrochloride shows antitumor activity .
Cat. No.: HY-147289
CAS No.: 908069-17-0
Target:
Research Areas:
NSC 698600 is a potent PCAF inhibitor, with IC50 of 6.51 µM (PCAF/H31-21). NSC 698600 exhibits good activity of inhibiting the proliferation of cancer cells .
Cat. No.: HY-101125B
CAS No.: 2084850-77-9
Synonyms: D-45
Target:
Research Areas:
D-Moses (D-45) is an enantiomer of L-Moses (HY-101125). L-Moses (L-45) is a potent and selective p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor. D-Moses shows no observable binding for PCAF Brd. D-Moses can be used as an inactive control compound to L-Moses .
Cat. No.: HY-181279
CAS No.: 1209224-91-8
Research Areas:
PCAF/GCN5 ligand 1 is a PCAF/GCN5 ligand with high binding affinity. PCAF/GCN5 ligand 1 shows no functional effect on PCAF/GCN5 activity. PCAF/GCN5 ligand 1 undergoes optimization into a potent and selective PCAF/GCN5 ligand GSK4027 (HY-101027) .
Cat. No.: HY-RS07077
Target:
Research Areas:
KAT2B Human Pre-designed siRNA Set A contains three designed siRNAs for KAT2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07078
Target:
Research Areas:
Kat2b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kat2b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07079
Target:
Research Areas:
KAT2B Rat Pre-designed siRNA Set A contains three designed siRNAs for KAT2B gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-115829
CAS No.: 1610362-93-0
APA-H-MPO hydrochloride is an inhibitor of PCAF bromodomain/Tat-AcK50 interaction with potential for anti-HIV/AIDS. APA-H-MPO hydrochloride can effectively inhibit the binding of PCAF bromodomain to Tat-AcK50. APA-H-MPO hydrochloride showed low cytotoxicity in preliminary cell studies. APA-H-MPO hydrochloride is considered a potential candidate for a promising inhibitory strategy targeting the host cell protein PCAF BRD to block HIV replication .
Cat. No.: HY-115828
CAS No.: 1610362-98-5
APA-APA-MPO dihydrochloride is an inhibitor of PCAF bromodomain/Tat-AcK50 interaction with reduced cytotoxic activity. APA-APA-MPO dihydrochloride can effectively inhibit the binding of PCAF to Tat-AcK50, showing its potential in HIV/AIDS inhibitory strategies. APA-APA-MPO dihydrochloride can be used in studies that hinder HIV replication .
Cat. No.: HY-128597
CAS No.: 2351938-32-2
Research Areas:
BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ .
Cat. No.: HY-P702904
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KAT2B; K(Lysine) Acetyltransferase 2B; Prev. PCAF; Histone Acetylase PCAF; P/CAF; GCN5L; P300/CBP-Associated Factor; GCN5; Spermidine Acetyltransferase KAT2B; CREBBP-Associated Factor; Histone Acetyltransferase KAT2B; CAF; Lysine Acetyltransferase 2B; His
Species:
Human
Source:
E. coli
Cat. No.: HY-185009
CAS No.: 2260944-69-0
Research Areas:
GSK702, a PROTAC, is a the less active cis-(S,S)-enantiomer of GSK983 (P300/CBP-associated factor (PCAF)/general control nonderepressible 5 (GCN5) PROTAC). GSK702 induces only a small decrease of PCAF protein levels. GSK702 binds to CRBN and causes a reduction of IL-1β in macrophages. GSK702 can be used for the study of inflammatory mediators .
Cat. No.: HY-101027R
CAS No.: 2079896-25-4
Research Areas:
GSK 4027 (Standard) is the analytical standard of GSK 4027 (HY-101027). This product is intended for research and analytical applications. GSK 4027 is a chemical probe for the PCAF/GCN5 bromodomain with an pIC50 of 7.4±0.11 for PCAF in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.
Cat. No.: HY-P83155A
Synonyms: GCN5; hGCN5; GCN5L2; PCAF-b
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
