2. Epigenetics
  3. Epigenetic Reader Domain Histone Acetyltransferase
  4. PCAF/GCN5 ligand 1

PCAF/GCN5 ligand 1 is a PCAF/GCN5 ligand with high binding affinity. PCAF/GCN5 ligand 1 shows no functional effect on PCAF/GCN5 activity. PCAF/GCN5 ligand 1 undergoes optimization into a potent and selective PCAF/GCN5 ligand GSK4027 (HY-101027).

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PCAF/GCN5 ligand 1

PCAF/GCN5 ligand 1 Chemical Structure

CAS No. : 1209224-91-8

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PCAF/GCN5 ligand 1 Related Antibodies

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Description

PCAF/GCN5 ligand 1 is a PCAF/GCN5 ligand with high binding affinity. PCAF/GCN5 ligand 1 shows no functional effect on PCAF/GCN5 activity. PCAF/GCN5 ligand 1 undergoes optimization into a potent and selective PCAF/GCN5 ligand GSK4027 (HY-101027)[1].

In Vitro

PCAF/GCN5 ligand 1 (Compound 8) (10 μM) binds to the purified PCAF bromodomain with low micromolar affinity and good ligand efficiency[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PCAF/GCN5 ligand 1 Related Antibodies
Molecular Weight

267.69

Formula

C12H11ClFN3O
CAS No.
SMILES

CN1N=CC(NCC2=CC=C(F)C=C2)=C(Cl)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PCAF/GCN5 ligand 1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PCAF/GCN5 ligand 11209224-91-8Epigenetic Reader DomainHistone AcetyltransferaseHATsHATPCAF/GCN5PCAF bromodomainPCAF/GCN5 bromodomainsInhibitorinhibitorinhibit

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PCAF/GCN5 ligand 1
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HY-181279
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