Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
caged
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "caged" in MCE Product Catalog:
Cat. No.: HY-124086
CAS No.: 1417436-52-2
Target:
Research Areas:
BHQ-O-5HT is a light-activated caged 5-HT protected by a BHQ group. When exposed to light at 365 or 740 nm, BHQ-O-5HT releases 5-HT through 1 or 2 photon excitation, respectively. BHQ-O-5HT can be manipulated in space and time to explore the role of 5-HT in regulating mood, appetite, memory, learning, and other cognitive functions .
Cat. No.: HY-115231
CAS No.: 1009832-82-9
Target:
Research Areas:
ci-IP3/PM is a caged and cell permeable derivative of IP3. ci-IP3/PM can induce Ca 2+ release from internal stores .
Target:
Research Areas:
RuBi-GABA is a new ruthenium-based caged GABA compound. RuBi-GABA photocleaves and releases GABA after being excited with visible wavelengths. RuBi-GABA produces gaba receptor-mediated currents .
Cat. No.: HY-N7502
CAS No.: 17241-59-7
Category:
Quinones Anthraquinones Other Diseases Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.
Target:
Cat. No.: HY-113770
CAS No.: 97791-84-9
Synonyms: Lys-Thr
Target:
Research Areas:
Cat. No.: HY-103298
CAS No.: 1315378-75-6
Target:
Research Areas:
MNI-caged kainate is a photoprotected neuroactive amino acid with the activity to generate large inward currents. MNI-caged kainate can be released at the resting membrane potential of Purkinje cells and generate significant inward currents. The release of MNI-caged kainate results in approximately 40% of the current being generated through AMPA receptor activation. MNI-caged kainate is used to study fast synaptic receptor mechanisms. The photorelease time of MNI-caged kainate is in the sub-microsecond range, making it suitable for investigating the mechanisms of fast synaptic transmission .
Cat. No.: HY-164264
CAS No.: 217176-91-5
Target:
Research Areas:
Caged MK801 (cMK801) is a selective, non-competitive, irreversible NMDA receptor open-channel blocker. NVOC cages are neuro pharmocologically compatible .
Cat. No.: HY-165424
CAS No.: 3036456-18-2
Target:
Cat. No.: HY-107717
CAS No.: 1227675-52-6
Target:
Research Areas:
MNI-caged-NMDA is a light-sensitive amino acid with rapid release properties suitable for use in the study of fast synaptic receptor mechanisms. MNI-caged-NMDA shows metered release of NMDA receptors, inducing rapid and sustained receptor activation in cerebellar interneurons. MNI-caged-NMDA is able to achieve rapid transient responses and generate large inward currents by local laser photolysis. The use of MNI-caged-NMDA can effectively study neurotransmitter signaling and its inhibitory effects on GABA-A receptors .
Cat. No.: HY-107520A
CAS No.: 2226362-29-2
Target:
Research Areas:
MNI-caged-L-glutamate TFA is an inert photolabile glutamate precursor. MNI-caged-L-glutamate TFA does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate TFA can be used for research on neurotransmitters .
Cat. No.: HY-165624A
CAS No.: 136296-40-7
Target:
Research Areas:
(S)-LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (S)-LY-41 is a potent and selective 5-HT1A receptor agonist. (S)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (S)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (S)-LY-41 can induce the 5-HT behavioral syndrome. (S)-LY-41can be used for the research of neurological disease, such as depression and anxiety .
Cat. No.: HY-165624B
CAS No.: 136296-43-0
Target:
Research Areas:
(R)-LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41 (HY-165624A). (R)-LY-41 can be used for the research of neurological disease, such as depression and anxiety .
Cat. No.: HY-103300
CAS No.: 1186195-63-0
Target:
Research Areas:
NPE-caged-proton is a reagent that releases protons under UV light and has the activity of activating the fusion protein GP64 under weak acidic conditions. NPE-caged-proton can promote the binding of enveloped viruses to liposome membranes with acidic phospholipids in an environment of pH 4.0 to 5.5, thereby initiating membrane fusion. The ultraviolet unblocking effect of NPE-caged-proton can lower the environmental pH, thereby triggering the process of viral membrane fusion. When studying the interaction between viruses and cell membranes, NPE-caged-proton provides a valuable tool for revealing the subtle behaviors of viruses in different chemical and biochemical environments .
Cat. No.: HY-103467
CAS No.: 223759-19-1
Target:
Research Areas:
NPE-caged-HPTS sodium is a caged fluorophore that fluoresces upon uncaged fluorophore release, releasing the free highly polar fluorophore HPTS (Exc=470/40 nm, Em=525/50 nm). HPTS releases the fluorophore rapidly and uniformly, allowing for measurement of diffusion within tissues, with a diffusion coefficient of μm 2s -1, similar to that of synaptic L-glutamate .
Cat. No.: HY-103555
CAS No.: 1315379-60-2
Target:
Research Areas:
NPEC-caged-(1S,3R)-ACPD is a specific photosensitive ligand for glutamate receptor subtypes.
Category:
Target:
Cat. No.: HY-RS01825
Target:
Research Areas:
CAGE1 Human Pre-designed siRNA Set A contains three designed siRNAs for CAGE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-159110
CAS No.: 1947375-16-7
Target:
Research Areas:
ABA-DMNB is a photo-caged chemically induced proximity (CIP) inducer. ABA-DMNB is a photo-caged ABA (Abscisic acid (HY-100560)). ABA-DMNB can be uncaged under light irradiation and generate active ABA .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
