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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
128 Results for "
pgf2
" in MedChemExpress (MCE) Product Catalog:
Products (128)
128 Results for "pgf2" in MCE Product Catalog:
Cat. No.: HY-129953A
CAS No.: 36150-01-3
Synonyms: 5-trans pgf2α
Target:
Research Areas:
5-trans Prostaglandin F2α is an endogenous metabolite present in Blood that can be used for the research of Myocardial Infarction [2].
Cat. No.: HY-107381A
CAS No.: 62561-03-9
Synonyms: D-Cloprostenol sodium
Target:
Research Areas:
(+)-Cloprostenol sodium is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.
Cat. No.: HY-129953F
Synonyms: pgf2α-biotin
Cat. No.: HY-114867
CAS No.: 1163135-92-9
Synonyms: 15(R)-17-phenyl trinor pgf2α ethyl amide
Target:
Research Areas:
(15R)-Bimatoprost (15(R)-17-phenyl trinor PGF2α ethyl amide) is a prostaglandin analog used to study glaucoma and ocular hypertension. (15R)-Bimatoprost is an isomer of Bimatoprost with an inverted (β) hydroxyl group on C-15 .
Cat. No.: HY-116161
CAS No.: 130273-87-9
Target:
Research Areas:
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
Cat. No.: HY-132277
CAS No.: 1163135-96-3
Target:
Research Areas:
15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive .
Cat. No.: HY-172574
Synonyms: 8-iso-17-Phenyl trinor pgf2α
Target:
Research Areas:
8-Iso-17-phenyl trinor prostaglandin F2α (8-Iso-17-phenyl trinor PGF2), the C-8 epimer of Bimatoprost (HY-B0191), is a PGF2α (HY-12956) analog. Bimatoprost can be used in the research of glaucoma and high intraocular pressure.
Cat. No.: HY-106037
CAS No.: 53764-90-2
Target:
Research Areas:
PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation .
Cat. No.: HY-137547
CAS No.: 57930-92-4
Target:
Research Areas:
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
Cat. No.: HY-125396
CAS No.: 37786-07-5
Synonyms: 11-Deoxy-pgf2β
Target:
Cat. No.: HY-137544
CAS No.: 38315-48-9
Synonyms: 16-Phenyl tetranor pgf2α
Research Areas:
16-phenyl tetranor Prostaglandin F2α (16-phenyl tetranor PGF2α) is a metabolically stable analog of PGF2α. The affinity of 16-phenyl tetranor PGF2α at the FP receptor of ovine luteal cells is poor (8.7%) compared to PGF2α.
Cat. No.: HY-W746888
CAS No.: 1176637-26-5
Synonyms: 17-p-pgf2α-NEt2; 17-Phenyl trinor pgf2α diethyl amide
Target:
Research Areas:
17-Phenyl trinor prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is a PGF2α analog with hypotensive efficacy .
Cat. No.: HY-137412
CAS No.: 55314-49-3
Synonyms: Prostaglandin F2α 1,15-lactone
Target:
Research Areas:
PGF2α 1,15-lactone (Prostaglandin F2α 1,15-lactone) is a lipid-soluble internal ester of PGF2α. PGF2α 1,15-lactone decreases menstrual cycle lengths in non-pregnant rhesus monkeys. PGF2α 1,15-lactone terminates early pregnancy in the monkey .
Cat. No.: HY-116549
CAS No.: 13261-27-3
Synonyms: pgf2α alcohol
Target:
Research Areas:
Prostaglandin F2α alcohol (PGF2α alcohol) is an analog of PGF2α. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist .
Cat. No.: HY-139063
CAS No.: 51705-19-2
Synonyms: 16-Phenoxy tetranor pgf2α
Research Areas:
16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.
Cat. No.: HY-136627
CAS No.: 291303-34-9
Target:
Research Areas:
PGF2α analogue-1 is an analog of Dinoprost (HY-12956) containing an acetylenic fluorobenzene substituent in the lower side chain.
Cat. No.: HY-114841
CAS No.: 27376-74-5
Synonyms: 13,14-Dihydrodinoprost; 13,14-dihydro pgf2α
Target:
Research Areas:
13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 μg/100 g.
Cat. No.: HY-114850
CAS No.: 36150-02-4
Synonyms: 5-trans-pgf2β
Target:
Research Areas:
5-trans Prostaglandin F2β (5-trans-PGF2β) is the 9β-hydroxy isomer of 5-trans PGF2α .
Cat. No.: HY-116051
CAS No.: 39746-23-1
Synonyms: 16,16-Dimethyl-pgf2α
Target:
Research Areas:
16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor [2].
Cat. No.: HY-118648
CAS No.: 33854-16-9
Synonyms: pgf2α methyl ester; Dinoprost methyl
Target:
Research Areas:
Prostaglandin F2α methyl ester (PGF2α methyl ester; Dinoprost methyl) is a PGF2α analog with more lipid solubility. Prostaglandin F2α methyl ester exhibits efficacy in maintaining the ocular hypotensive .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
