27376-74-5
Chemical Structure
ONO 207
Synonym(s): 13,14-Dihydrodinoprost; 13,14-dihydro PGF2α
- CAS No.: 27376-74-5
- Formula:C20H36O5
- Molecular Weight:356.50
IUPAC Name: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-3-hydroxyoctyl)cyclopentyl)hept-5-enoic acid
InChIKey: LLQBSJQTCKVWTD-NFUXFLSFSA-N
SMILES: O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CC[C@H](CCCCC)O)C/C=C\CCCC(O)=O
Biological Activity: 13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 μg/100 g.
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ONO 207 | 13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 μg/100 g. | |||||||||||||||||||||
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